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A0A343CEI6 · A0A343CEI6_TRANA

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    A0A343CEI6

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane21-42Helical
Transmembrane54-73Helical
Transmembrane94-110Helical
Transmembrane116-133Helical
Transmembrane145-167Helical
Transmembrane193-216Helical
Transmembrane223-244Helical
Transmembrane256-277Helical
Transmembrane284-303Helical
Transmembrane309-330Helical
Transmembrane351-373Helical
Transmembrane393-414Helical

Keywords

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-109NADH:ubiquinone oxidoreductase chain 4 N-terminal
Domain112-398NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    459
  • Mass (Da)
    51,810
  • Last updated
    2018-11-07 v1
  • MD5 Checksum
    2A47CF31DE6A705BF66D362BD8314BDF
MLKFIMPTMMLLPLTWLSKNNMIWINTTAHSLLISLTSLILLNQHGDNSLNFSLTFFSDSLSTPLLILTTWLLPLMIMASQNHLSKEPLTRKKLYISMLTTLQLLLIMTFTATELILFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLVGSLPLLVALVYIQNTTGSLNFLILHYWSQPLPNSWSNVFMWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAILLKLGGYGMLRITTILNPITDFMAYPFILLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSFMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMAAWWLLASLTNLALPPSINLIGELFVIMSTFSWSNTTIILMGLNMIITALYSLYMLITTQRGKHTHHINNILPSFTRENALMSLHMLPLLLLSLNPKIILGPMY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KY117549
EMBL· GenBank· DDBJ
ARM56479.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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