A0A2W5SW42 · A0A2W5SW42_9CORY

Function

function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site103Proton donor/acceptor
Active site166Schiff-base intermediate with acetaldehyde
Active site196Proton donor/acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functiondeoxyribose-phosphate aldolase activity
Molecular Functionmagnesium ion binding
Molecular Functionphosphopentomutase activity
Biological Process2-deoxyribose 1-phosphate catabolic process
Biological Processcarbohydrate metabolic process
Biological Processdeoxyribonucleotide catabolic process
Biological Processpurine ribonucleoside salvage

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Deoxyribose-phosphate aldolase
  • EC number
  • Short names
    DERA
  • Alternative names
    • 2-deoxy-D-ribose 5-phosphate aldolase
    • Phosphodeoxyriboaldolase
      (Deoxyriboaldolase
      )

Gene names

    • Name
      deoC
    • ORF names
      DI525_09100

Organism names

  • Taxonomic identifier
  • Strain
    • S2_003_000_R1_3
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium

Accessions

  • Primary accession
    A0A2W5SW42

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-19Polar residues
Region1-20Disordered
Domain285-426Alpha-D-phosphohexomutase alpha/beta/alpha
Region457-484Disordered
Compositional bias464-481Basic and acidic residues
Domain486-571Alpha-D-phosphohexomutase alpha/beta/alpha
Region572-594Disordered
Domain637-725Alpha-D-phosphohexomutase alpha/beta/alpha
Domain777-815Alpha-D-phosphohexomutase C-terminal

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
Belongs to the phosphohexose mutase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    851
  • Mass (Da)
    89,752
  • Last updated
    2018-09-12 v1
  • MD5 Checksum
    53792C953C6B24BA33AA264277F894D8
MPTTPDSLSSGTNHTPSRDEVASIVDHTLLKPESTHHDVDELIHEATELGTYSICVSPSMLPVTVPDGLHVAAVCGFPSGAHASEIKAEEARLAVKNGADEIDMVINMAAAAEGDWATVEKDIRAVRDAVPSPTVLKVILETALLSDDAIVAACKAAKNAGADFVKTSTGFHPSGGASAHAIRLIRETVGPDMGVKASGGIRTAEKALEMIAAGANRLGLSGTRAVLDGLADSSESDDSTYDDILARAEKWADSDVDSTDAETIRELIKTRNIDELAARFSGPLQFGTAGLRGEIGAGESRMNRSVIIKATAGLVSYLTESIGSAPVVVIGHDARHGSAEFATDAAEVINAAGGHALRLPSHLPTPLLAFAVRHLKADAGIMVTASHNPPRDNGYKVYLGGRMTDQWGNGVQIVPPDDSNIANAIAQTGPAEDIPRSSEGITFLGEEVREAYLAALETETEPFRTSETASKGDDSSTSDESHSSFHSDISITLTAMHGVGAETATKALNKAGFTNITLVKEQAEPDPDFPTVSFPNPEEKGALDLALSTAQRSQANVVIALDPDADRCSVAIPTKTSDTTGSDGSSTEPTYRQLTGDQIGGLLGDFVTRTKLRPVHQNSGSNSDAASGDATAETSDSVFANSIVSSRLLGAIASKYDLNYGPTLTGFKWIGRTPDLAFGYEEAIGYCTYPHIVRDKDGVSAAVTVAYLVDSLHREGKTVDDRLTEITRDNGVYATTQAAFRVENRQRIVDGMSKLRTTPPAEFAGSPITEFADLADGYHGLPGTDGVLFLTEDNTRVICRPSGTEPKLKCYLEVVLPVDKDATTTEIMALQTQAQAKLEQIRAEITVATGF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-19Polar residues
Compositional bias464-481Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QFRA01000029
EMBL· GenBank· DDBJ
PZR03756.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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