A0A2W5SW42 · A0A2W5SW42_9CORY
- ProteinDeoxyribose-phosphate aldolase
- GenedeoC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids851 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
Catalytic activity
- 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
Cofactor
Pathway
Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 103 | Proton donor/acceptor | |||
Active site | 166 | Schiff-base intermediate with acetaldehyde | |||
Active site | 196 | Proton donor/acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | deoxyribose-phosphate aldolase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | phosphopentomutase activity | |
Biological Process | 2-deoxyribose 1-phosphate catabolic process | |
Biological Process | carbohydrate metabolic process | |
Biological Process | deoxyribonucleotide catabolic process | |
Biological Process | purine ribonucleoside salvage |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDeoxyribose-phosphate aldolase
- EC number
- Short namesDERA
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium
Accessions
- Primary accessionA0A2W5SW42
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-19 | Polar residues | |||
Region | 1-20 | Disordered | |||
Domain | 285-426 | Alpha-D-phosphohexomutase alpha/beta/alpha | |||
Region | 457-484 | Disordered | |||
Compositional bias | 464-481 | Basic and acidic residues | |||
Domain | 486-571 | Alpha-D-phosphohexomutase alpha/beta/alpha | |||
Region | 572-594 | Disordered | |||
Domain | 637-725 | Alpha-D-phosphohexomutase alpha/beta/alpha | |||
Domain | 777-815 | Alpha-D-phosphohexomutase C-terminal | |||
Sequence similarities
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
Belongs to the phosphohexose mutase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length851
- Mass (Da)89,752
- Last updated2018-09-12 v1
- MD5 Checksum53792C953C6B24BA33AA264277F894D8
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-19 | Polar residues | |||
Compositional bias | 464-481 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QFRA01000029 EMBL· GenBank· DDBJ | PZR03756.1 EMBL· GenBank· DDBJ | Genomic DNA |