A0A2T5GCT0 · A0A2T5GCT0_HYDSH

Function

function

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site19-26ATP (UniProtKB | ChEBI)
Binding site21-26substrate
Site110Interaction with substrate tRNA
Site134Interaction with substrate tRNA

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctiontRNA dimethylallyltransferase activity
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA dimethylallyltransferase
  • EC number
  • Alternative names
    • Dimethylallyl diphosphate:tRNA dimethylallyltransferase
      (DMAPP:tRNA dimethylallyltransferase
      ; DMATase
      )
    • Isopentenyl-diphosphate:tRNA isopentenyltransferase
      (IPP transferase
      ; IPPT
      ; IPTase
      )

Gene names

    • Name
      miaA
    • ORF names
      HSCHL_0855

Organism names

Accessions

  • Primary accession
    A0A2T5GCT0

Proteomes

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region44-47Interaction with substrate tRNA

Sequence similarities

Belongs to the IPP transferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    326
  • Mass (Da)
    36,167
  • Last updated
    2018-07-18 v1
  • MD5 Checksum
    038D4E636323785A2553CFEAE9AC91FE
MTGSEAGGRPDGVLIALVGPTAVGKTALSLELAERFDGEIVSADSMQVYRGMDIGTAKATPEERARIRHHLIDVADPRERYSVARYQREALAAIRDIRARGKVPFLVGGTGLYVNAVVYYPQYRFAPGSPGVLRRRLVERARREGAHALWQELSIRAPEVARRIPANDVRRIVRALEMLAGEGAGLLPNAPPPERKSPFHLLMIGLTMRREALYRAIEARVEAQIAAGLLDEVRRLLAAGVPPEATALQALGYKELLGVVRGEESLEAAVARIKRRTRQYAKRQLTWFRRLPDIEWVPWDEDVRPDSRPKIFARVAGHLAADGESL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PEBV01000007
EMBL· GenBank· DDBJ
PTQ54001.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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