A0A2S0MKI6 · A0A2S0MKI6_9RHOB

  • Protein
    Adenosine 5'-phosphosulfate reductase
  • Gene
    cysH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster per subunit.

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site124[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site125[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site205[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site208[4Fe-4S] cluster (UniProtKB | ChEBI)
Active site231Nucleophile; cysteine thiosulfonate intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionadenylyl-sulfate reductase (thioredoxin) activity
Molecular Functionmetal ion binding
Molecular Functionphosphoadenylyl-sulfate reductase (thioredoxin) activity
Biological Processsulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosine 5'-phosphosulfate reductase
  • EC number
  • Short names
    APS reductase
  • Alternative names
    • 5'-adenylylsulfate reductase
    • Thioredoxin-dependent 5'-adenylylsulfate reductase

Gene names

    • Name
      cysH
    • ORF names
      C6Y53_00130

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SH-1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Pukyongiella

Accessions

  • Primary accession
    A0A2S0MKI6

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for coiled coil, domain.

Type
IDPosition(s)Description
Coiled coil1-28
Domain45-211Phosphoadenosine phosphosulphate reductase

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    245
  • Mass (Da)
    27,327
  • Last updated
    2018-07-18 v1
  • MD5 Checksum
    FB32BA473EB7160EAC894D2513C9EA7A
MQFETNARRELRERAEALSTQHAGLQAEAVLASVLRDIYPGRVGLVSSFGTEAAVLLHMVAQIDPYAPVIFLETGKHFPETLDYRETLARELGLCNLQVVSPRPASVAADDPDGDLHARNPDLCCHVRKTLPMLQALRGLSCWITGRKRYQAATRDELALFEAQDRWIKVNPILDWDRDRIADYFRTHDLPRHPLEAQGYPSIGCAPCTSAVREGDDPRAGRWAGSDKTECGIHFENGKLVRKGG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP027665
EMBL· GenBank· DDBJ
AVO36271.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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