A0A2I1EDD6 · A0A2I1EDD6_9GLOM
- ProteintRNA-dihydrouridine(47) synthase [NAD(P)(+)]
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids669 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.
Catalytic activity
- 5,6-dihydrouridine47 in tRNA + NAD+ = uridine47 in tRNA + NADH + H+This reaction proceeds in the backward direction.
- a 5,6-dihydrouridine in mRNA + NAD+ = a uridine in mRNA + NADH + H+This reaction proceeds in the backward direction.
- a 5,6-dihydrouridine in mRNA + NADP+ = a uridine in mRNA + NADPH + H+This reaction proceeds in the backward direction.
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | metal ion binding | |
Molecular Function | RNA binding | |
Molecular Function | tRNA-dihydrouridine47 synthase activity | |
Biological Process | mRNA processing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-dihydrouridine(47) synthase [NAD(P)(+)]
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Mucoromycota > Glomeromycotina > Glomeromycetes > Glomerales > Glomeraceae > Rhizophagus
Accessions
- Primary accessionA0A2I1EDD6
Proteomes
Organism-specific databases
Structure
Family & Domains
Features
Showing features for region, domain, zinc finger, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 34-67 | Disordered | |||
Domain | 112-137 | C3H1-type | |||
Zinc finger | 112-137 | C3H1-type | |||
Compositional bias | 193-214 | Basic and acidic residues | |||
Region | 193-225 | Disordered | |||
Sequence similarities
Belongs to the dus family. Dus3 subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length669
- Mass (Da)76,682
- Last updated2018-02-28 v1
- MD5 ChecksumCAD706EFA152EFD9393F721C12D79858
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 193-214 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAGKOT010000018 EMBL· GenBank· DDBJ | CAB5363551.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LLXH01001083 EMBL· GenBank· DDBJ | PKC60825.1 EMBL· GenBank· DDBJ | Genomic DNA |