A0A2A9E188 · A0A2A9E188_9MICO
- ProteinRelease factor glutamine methyltransferase
- GeneprmC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids313 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
Catalytic activity
- L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 152 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 202 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 202-205 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | nucleic acid binding | |
Molecular Function | protein-(glutamine-N5) methyltransferase activity | |
Molecular Function | protein-glutamine N-methyltransferase activity | |
Biological Process | peptidyl-glutamine methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRelease factor glutamine methyltransferase
- EC number
- Short namesRF MTase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Sanguibacteraceae > Sanguibacter
Accessions
- Primary accessionA0A2A9E188
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 7-80 | Release factor glutamine methyltransferase N-terminal | |||
Domain | 117-206 | Methyltransferase small | |||
Sequence similarities
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length313
- Mass (Da)32,344
- Last updated2017-12-20 v1
- MD5 Checksum8D6C17471654282A9227846D93D8F2FE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PDJG01000001 EMBL· GenBank· DDBJ | PFG32613.1 EMBL· GenBank· DDBJ | Genomic DNA |