A0A2A4IN99 · A0A2A4IN99_9SPIR
- ProteinPolyamine aminopropyltransferase
- GenespeE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids286 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
Catalytic activity
- S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H+
Pathway
Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 31 | S-methyl-5'-thioadenosine (UniProtKB | ChEBI) | |||
Binding site | 62 | spermidine (UniProtKB | ChEBI) | |||
Binding site | 86 | spermidine (UniProtKB | ChEBI) | |||
Binding site | 106 | S-methyl-5'-thioadenosine (UniProtKB | ChEBI) | |||
Binding site | 137-138 | S-methyl-5'-thioadenosine (UniProtKB | ChEBI) | |||
Active site | 156 | Proton acceptor | |||
Binding site | 156-159 | spermidine (UniProtKB | ChEBI) | |||
Binding site | 163 | S-methyl-5'-thioadenosine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | spermidine synthase activity | |
Biological Process | spermidine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyamine aminopropyltransferase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Spirochaetota > Spirochaetia > Brachyspirales > Brachyspiraceae > Brachyspira
Accessions
- Primary accessionA0A2A4IN99
Proteomes
Interaction
Subunit
Homodimer or homotetramer.
Structure
Sequence
- Sequence statusComplete
- Length286
- Mass (Da)33,257
- Last updated2017-12-20 v1
- Checksum4AAA3935726F5EC1
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JQIU01000008 EMBL· GenBank· DDBJ | PCG19372.1 EMBL· GenBank· DDBJ | Genomic DNA |