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A0A2A3MQJ0 · A0A2A3MQJ0_9SPHN

  • Protein
    Peroxisomal trans-2-enoyl-CoA reductase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • (2E)-decenoyl-CoA + NADPH + H+ = decanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-dodecenoyl-CoA + NADPH + H+ = dodecanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-hexenoyl-CoA + NADPH + H+ = hexanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-octenoyl-CoA + NADPH + H+ = octanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-tetradecenoyl-CoA + NADPH + H+ = tetradecanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • a (2E)-enoyl-CoA + NADPH + H+ = a 2,3-saturated acyl-CoA + NADP+
    This reaction proceeds in the forward direction.
    EC:1.3.1.38 (UniProtKB | ENZYME | Rhea)

Pathway

Lipid metabolism.

GO annotations

AspectTerm
Cellular Componentperoxisome
Molecular Functiontrans-2-enoyl-CoA reductase (NADPH) activity
Biological Processphytol metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peroxisomal trans-2-enoyl-CoA reductase
  • EC number

Gene names

    • ORF names
      SxD43FB_20260

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • D43FB
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingobium

Accessions

  • Primary accession
    A0A2A3MQJ0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Interacts with PEX5, probably required to target it into peroxisomes.

Family & Domains

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    261
  • Mass (Da)
    27,516
  • Last updated
    2017-12-20 v1
  • MD5 Checksum
    8213CA5CBFE9B52E7E787C86BE9F300A
MTSTRRFDKQVAVVTGGAQGIGLATATRMAEEGAIVIVADRAVEATRAAVERLQTSGANVHAANFDLETCEGAVELYRLVADRFGRIDVAVHNVGGTIWAKPYWDYTSDEIIAEINRSLWPTLWSCHAVLPFMLAAGRGSIVNIGSVATRGVNRVPYAAAKGGVAALTAALSLELETSGVRINCVAPGGVNVTRVTPRDPVPMTDAVKSGFVKVMEQTVRDTPMARFGEPEELAAAICFFASEEASYITGQTLFVAGGGIG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NMUA01000037
EMBL· GenBank· DDBJ
PBN41722.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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