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A0A2A2H9G0 · A0A2A2H9G0_METBR

  • Protein
    Tetrahydromethanopterin S-methyltransferase subunit A
  • Gene
    mtrA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

5-hydroxybenzimidazolylcob(I)amide (UniProtKB | Rhea| CHEBI:60494 )

Note: Binds 1 5-hydroxybenzimidazolylcobamide group.

Pathway

One-carbon metabolism; methanogenesis from CO2; methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site845-hydroxybenzimidazolylcob(I)amide (UniProtKB | ChEBI); cofactor

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncobalt ion binding
Molecular Functiontetrahydromethanopterin S-methyltransferase activity
Biological Processmethanogenesis, from carbon dioxide
Biological Processmethylation
Biological Processone-carbon metabolic process
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tetrahydromethanopterin S-methyltransferase subunit A
  • EC number
  • Alternative names
    • N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A

Gene names

    • Name
      mtrA
    • ORF names
      ASJ80_14040

Organism names

  • Taxonomic identifier
  • Strain
    • M.o.H.
  • Taxonomic lineage
    Archaea > Euryarchaeota > Methanomada group > Methanobacteria > Methanobacteriales > Methanobacteriaceae > Methanobacterium

Accessions

  • Primary accession
    A0A2A2H9G0

Proteomes

Subcellular Location

Cell membrane
; Single-pass membrane protein

Keywords

Interaction

Subunit

The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

Family & Domains

Sequence similarities

Belongs to the MtrA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    198
  • Mass (Da)
    21,642
  • Last updated
    2017-12-20 v1
  • MD5 Checksum
    1A5B7E4DDF1E2ACD8362C91933ABA223
MVEKKKTAEGWPVVNGDYVVGNPKSCVAGATLASHLEDVIVDAGAAIAGPVKTENLGIEKMIANLISNPNIRFLLLCGSEVQGHITGQSIEALHANGVAPDKRRIVGATGAIPYIENVPDEAIDRFRQQLEIVSLIDSEDMDLIRARVKECVEKDPGAAEEETVIIQLEENCEEVKVVKSTSETDLIYSRRRYRKMNT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LMVM01000001
EMBL· GenBank· DDBJ
PAV05966.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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