A0A254NBX9 · A0A254NBX9_9BURK

  • Protein
    Catalase-peroxidase
  • Gene
    katG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site98Transition state stabilizer
Active site102Proton acceptor
Binding site270Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      CDO81_07240

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CCUG 52769
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Sphaerotilaceae > Roseateles

Accessions

  • Primary accession
    A0A254NBX9

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link229↔255Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-27Disordered
Domain135-431Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    740
  • Mass (Da)
    79,673
  • Last updated
    2017-11-22 v1
  • MD5 Checksum
    2837526E90ED41581C20108D3650052A
MSETPKTAAAQCPFHHGGSASPNRAATANQRWWPNQLNLAVLHQRAPKSNPMGESFDYAKAFQSLDLDAVVADLKALMTDSQDWWPADYGHYGPFFIRMAWHAAGTYRVADGRGGAGTGNQRFAPLNSWPDNGNLDKARRLLWPIKQKYGEKLSWADLFVLTGNVALESMGFKTFGFGGGREDIYEPEIDIDWGPEAEWLALSGTPNSRYSGERDLAHPLAAVQMGLIYVNPEGPDGNPDPLLSARDIRETFARMAMNDEETVALVAGGHTFGKAHGAGDPQHVGKEPEGADILDQGLGWKSSYASGMAGHTITSGLEGAWKPNPTTWDNGYFDTLFKYEWELTKSPAGAHQWTPKGGAGAGTVVDAHDPTKFHAPMMSTADLALRMDPAYEKISRRFHADPAAFADAFARAWFKLTHRDMGPINRYLGKLVPKETLIWQDPIPAVDHPLINAADIAALKAQVLASGLTTAQLVSTAWASAASFRGSDKRGGANGARIRLAPQKEWAVNQPAQLSTVLAKLEAIQQQFNASAAGGRKVSLADLIVLAGGAAVEAAAQAAGVPVEVPFHPGRMDATQDQTDVDSFAPLEPRADGFRNYLAPGLPEAAAAELLVDKAQLLTLAAPEMAVLVAGLRVLGANTGGSAHGVFTTRPGVLTNDFFVNLLDMRTQWKKNGDVLEGVDRSTGERKWTATIVDLVFGSNAQLRALAEVYAGSDASAKFVNDFVAAWTKVMELDRFDLHA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NISI01000002
EMBL· GenBank· DDBJ
OWR04382.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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