A0A238FCM3 · A0A238FCM3_9BASI

  • Protein
    Arginine biosynthesis bifunctional protein ArgJ, mitochondrial
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N2-acetyl-L-ornithine (cyclic): step 1/1.
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 1/4.

Features

Showing features for site, binding site, active site.

Type
IDPosition(s)Description
Site149Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Site150Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Binding site188substrate
Binding site214substrate
Site228-229Cleavage; by autolysis
Active site229Nucleophile
Binding site229substrate
Binding site317substrate
Binding site447substrate

GO annotations

AspectTerm
Cellular Componentmitochondrial matrix
Molecular Functionglutamate N-acetyltransferase activity
Molecular FunctionL-glutamate N-acetyltransferase activity
Biological Processarginine biosynthetic process
Biological Processornithine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Including 2 domains:

  • Recommended name
    Glutamate N-acetyltransferase
  • EC number
  • Short names
    GAT
  • Alternative names
    • Ornithine acetyltransferase
      (OATase
      )
    • Ornithine transacetylase
  • Recommended name
    Amino-acid acetyltransferase
  • EC number
  • Alternative names
    • N-acetylglutamate synthase
      (AGS
      )

Gene names

    • ORF names
      BQ2448_1913

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Pucciniomycotina > Microbotryomycetes > Microbotryales > Microbotryaceae > Microbotryum

Accessions

  • Primary accession
    A0A238FCM3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50235373061-228Arginine biosynthesis bifunctional protein ArgJ alpha chain
ChainPRO_5023537305229-450Arginine biosynthesis bifunctional protein ArgJ beta chain

Post-translational modification

The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.

Keywords

Interaction

Subunit

Heterodimer of an alpha and a beta chain.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-25Disordered

Sequence similarities

Belongs to the ArgJ family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    450
  • Mass (Da)
    47,257
  • Last updated
    2017-11-22 v1
  • Checksum
    7DCDDB15C8385666
MPPSSTTTRLKTSASSPLLSSSPQSKAQRLAFDPTAARFPLGFLATGLHCGIKKDPSRLDLGVIISDRPCSAAGTFTRNAFVAAPVVVSKDVLTKGRGVARGLVVNSGCANAVTGAQGLKDARAMSEQLDSFLSESNSSSATGTLVMSTGVIGQLLPIKKILNGITSSTATLGPTHSAWLDAAKAFMTTDTFPKLRTRSFQLGGKEVRMVGIDKGAGMIHPNMGPPHATLLGMIATDAAVTPASLQDALTYAVDRSFNSISVDGDMSTNDTIVVLANGASGSVEVSEKATPDEFIKFRDQLTDFAAELAQLVVRDGEGAEKFVKVTVKGAPTYEGAHKIASTISTSALVKCALHGEDANWGRILCAVGYSKPDFVIDPTKVTVSFVPVDGSPELRLLVNGEPEQVDEVRASEILKSEDLAIQVDLGLGEECATYWTCDFSHEYISINAGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FMSP01000005
EMBL· GenBank· DDBJ
SCV70519.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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