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A0A228I2A8 · A0A228I2A8_9BURK

Function

function

Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Mg2+. Can also accept Mn2+.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.

Features

Showing features for binding site, active site, site.

Type
IDPosition(s)Description
Binding site9Mg2+ (UniProtKB | ChEBI)
Binding site16ATP (UniProtKB | ChEBI)
Binding site93substrate
Active site150Proton donor/acceptor
Site181Transition state stabilizer
Binding site208-212ATP (UniProtKB | ChEBI)
Site241Transition state stabilizer
Binding site283-285ATP (UniProtKB | ChEBI)
Binding site328-332ATP (UniProtKB | ChEBI)
Binding site379Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionacetate kinase activity
Molecular FunctionATP binding
Molecular Functionmagnesium ion binding
Biological Processacetate metabolic process
Biological Processacetyl-CoA biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetate kinase
  • EC number
  • Alternative names
    • Acetokinase

Gene names

    • Name
      ackA
    • ORF names
      CFB84_34350

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • AU17325
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex

Accessions

  • Primary accession
    A0A228I2A8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the acetokinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    392
  • Mass (Da)
    41,836
  • Last updated
    2017-10-25 v1
  • MD5 Checksum
    8810C7BB310B095B744DC0074B9543FA
MADVILVLNAGSSSIKFSAFDVQGDTLGLIVHGQVDGLYTATAHFSAVDHHAERHERQWAGGASFGHHEGLAQIAAFLEDHQEGHRLAAVGHRVVHGGQRFSGPVRVTPEIVAELEKLTPLAPLHQPHNLTPIRILETVQPGIEQVACFDTAFHSTQPAVTQAFALPASITSRGVRRYGFHGLSYEYIASVLPAVAPQVARGRTVVAHLGNGASMCALVAGKSVASTMGFTAVDGLPMGTRCGNLDPGVVLFLMDELGMDVRAVEDLLYRRSGLLGVSGLSSDMRTLLASDDPHARFAIELYIYRIARELGSLAAAMEGIDAIVFTAGIGEHAAAIREGVLRRAAWLGVEIDVEANRADGPLIATASSRVPAWVIPTNEELMIAQHTLRLIR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NKFA01000023
EMBL· GenBank· DDBJ
OXI36544.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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