A0A220USS3 · A0A220USS3_9GAMM

  • Protein
    Protoheme IX farnesyltransferase
  • Gene
    cyoE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

Miscellaneous

Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionprotoheme IX farnesyltransferase activity
Biological Processheme O biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protoheme IX farnesyltransferase
  • EC number
  • Alternative names
    • Heme B farnesyltransferase
    • Heme O synthase

Gene names

    • Name
      cyoE
    • ORF names
      CF168_20355

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • JAB-1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella

Accessions

  • Primary accession
    A0A220USS3

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane21-43Helical
Transmembrane49-73Helical
Transmembrane94-114Helical
Transmembrane120-140Helical
Transmembrane147-169Helical
Transmembrane175-196Helical
Transmembrane222-239Helical
Transmembrane245-262Helical
Transmembrane274-295Helical

Keywords

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    310
  • Mass (Da)
    33,466
  • Last updated
    2017-11-22 v1
  • Checksum
    973848412D8E568A
MNTQARLTSTQWKARFKGYVQVTKPGIIFGNLISVAGGFLLAAKGDVDLVLMLASLVGLSLVVASGCAINNCIDRDIDAKMQRTCKRVTVTGEIPLSHVLLFGIALGVLGFGILALFTNALALLFAAIGYVVYVGIYSLYMKRNSVYGTLVGSFSGAVPPVVGYCSVTGQMDMGAVILLLMFSLWQMPHSYAIAIFRFNDYAAAKIPVLPVAEGMAKAKHHIVLYIAVFALVSTMLPLAGYTGTAFMAVTCATSLWWLTMALKGYRQDVDMPRWARQVFGFSIITITALSVTMALDFQAVSQTPLFTLVR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP022358
EMBL· GenBank· DDBJ
ASK71040.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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