A0A1V2KPG9 · A0A1V2KPG9_9ACTN

  • Protein
    Mycothiol acetyltransferase
  • Gene
    mshD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

134050100150200250300
TypeIDPosition(s)Description
Binding site361D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site79-81acetyl-CoA 1 (UniProtKB | ChEBI)
Binding site2061D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site2451D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site2661D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site270-272acetyl-CoA 2 (UniProtKB | ChEBI)
Binding site277-283acetyl-CoA 2 (UniProtKB | ChEBI)
Binding site3041D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI)
Binding site309-314acetyl-CoA 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmycothiol synthase activity
Molecular Functionpeptide-alanine-alpha-N-acetyltransferase activity
Biological Processmycothiol biosynthetic process
Biological ProcessN-terminal peptidyl-alanine acetylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mycothiol acetyltransferase
  • EC number
  • Short names
    MSH acetyltransferase
  • Alternative names
    • Mycothiol synthase

Gene names

    • Name
      mshD
    • ORF names
      CcI49_16840

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CcI49
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Frankiales > Frankiaceae > Frankia

Accessions

  • Primary accession
    A0A1V2KPG9

Proteomes

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain5-148N-acetyltransferase
Compositional bias146-165Polar residues
Region146-175Disordered
Domain179-340N-acetyltransferase

Sequence similarities

Belongs to the acetyltransferase family. MshD subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    340
  • Mass (Da)
    35,449
  • Last updated
    2017-06-07 v1
  • MD5 Checksum
    0DC75E9970B6EA6CFC3018E111E19816
MTSLSWLDTLDATDVAAITELLTSAEQVDGNGGISEDVRLTLRPGGSPGGVAHLVARDGSTIVGFAAVGGDPSERQAELVVHPDHRRAGVGSALVRELSAAVAGSSQLNIWAHGDAPAAAALAGSAGFERARVLLQLRRPLIAASSATPGSATAGSATTGSATAAADDDLPSPTVPPGFTLRTFEVGRDEEAWLAINAAAFATHPEQGRWTMDDLRAREAEPWFDPAGFFLAERNGQLVGFHWTKVHPIDPMPAGDPQAAPGPIGEVYVVGVAPDAGGAGLGRILTIAGLRHLRDLGLATVMLYVDEDNDRAVRLYTRLGFHRHTADVSYQRVAPGRDRG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias146-165Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MOWP01000017
EMBL· GenBank· DDBJ
ONH59618.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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