A0A1T4JZ99 · A0A1T4JZ99_9FIRM

Function

function

Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).

Catalytic activity

Features

Showing features for binding site.

140550100150200250300350400
TypeIDPosition(s)Description
Binding site34L-tyrosine (UniProtKB | ChEBI)
Binding site167L-tyrosine (UniProtKB | ChEBI)
Binding site171L-tyrosine (UniProtKB | ChEBI)
Binding site230ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionRNA binding
Molecular Functiontyrosine-tRNA ligase activity
Biological Processtyrosyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine--tRNA ligase
  • EC number
  • Alternative names
    • Tyrosyl-tRNA synthetase
      (TyrRS
      )

Gene names

    • Name
      tyrS
    • ORF names
      SAMN02745110_00048

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ATCC 17233
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Eubacteriales > Eubacteriaceae > Eubacterium

Accessions

  • Primary accession
    A0A1T4JZ99

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for motif, domain.

Type
IDPosition(s)Description
Motif39-48'HIGH' region
Motif227-231'KMSKS' region
Domain324-400Tyrosine--tRNA ligase SYY-like C-terminal

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    405
  • Mass (Da)
    45,724
  • Last updated
    2017-05-10 v1
  • Checksum
    E2DF66DCB15EC43B
MELYEELVARGLIAQVTNEEEIKKLINTGKATFYIGFDPTADSLHVGHFMALCLMKRLQEGGNKPIALVGGGTGMIGDPSGRTDMRLMMTKETIDHNCECFKKQMSRFIDFSEGKALMVNNADWLMDLNYIEFIRDIGSQFSVNKMLAAECYKQRLERGLNFLEFNYMLMQSYDFLMLYEKYGCNLEFGGDDQWSNMLGGTELIRKKLGKDAHAMTITLLLNSEGKKMGKTAKGAVWLDPNKTSPFDFYQYWRNVDDKDVIKCLKMLTFLPIEEIQAMEVWEGAELNKAKEILAYELTKLVHGEEEAEKAQSAAKNIFSAGSSENMPETSLSDEDFVDGKVDLIGILVKAGLVKSRSEGRRAIEQGGVVVNDEKIVDVYASYTKDAFGADFIVRRGKKNFRKITL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FUXA01000003
EMBL· GenBank· DDBJ
SJZ35493.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help