A0A1I2T1M7 · A0A1I2T1M7_9FIRM
- ProteinATP-dependent Clp protease ATP-binding subunit ClpX
- GeneclpX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids434 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 11 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 14 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 34 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 37 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 117-124 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | HslUV protease complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATP-dependent protein folding chaperone | |
Molecular Function | peptidase activity | |
Molecular Function | protein dimerization activity | |
Molecular Function | unfolded protein binding | |
Molecular Function | zinc ion binding | |
Biological Process | cell division | |
Biological Process | proteolysis involved in protein catabolic process |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameATP-dependent Clp protease ATP-binding subunit ClpX
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Oribacterium
Accessions
- Primary accessionA0A1I2T1M7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-53 | ClpX-type ZB | |||
Region | 415-434 | Disordered | |||
Sequence similarities
Belongs to the ClpX chaperone family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length434
- Mass (Da)47,874
- Last updated2017-11-22 v1
- Checksum176B5F040A286C49
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FOPH01000013 EMBL· GenBank· DDBJ | SFG57067.1 EMBL· GenBank· DDBJ | Genomic DNA |