A0A1H9ADD2 · A0A1H9ADD2_9FLAO

  • Protein
    Allosteric NADP-dependent malic enzyme
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, active site.

1764100200300400500600700
Type
IDPosition(s)Description
Binding site77-84NADP+ (UniProtKB | ChEBI)
Active site95Proton acceptor
Binding site137a divalent metal cation (UniProtKB | ChEBI)
Binding site138a divalent metal cation (UniProtKB | ChEBI)
Binding site163a divalent metal cation (UniProtKB | ChEBI)
Binding site287a divalent metal cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionacyltransferase activity
Molecular Functionmalic enzyme activity
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Processmalate metabolic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Allosteric NADP-dependent malic enzyme

Gene names

    • ORF names
      SAMN05421824_0209

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 21035
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae

Accessions

  • Primary accession
    A0A1H9ADD2

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain19-152Malic enzyme N-terminal
Domain164-400Malic enzyme NAD-binding

Sequence similarities

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
In the N-terminal section; belongs to the malic enzymes family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    764
  • Mass (Da)
    84,870
  • Last updated
    2017-11-22 v1
  • Checksum
    583AE9E7FF6B4481
MSEESKRREALIYHAKPTPGKIKVVPTKKYASQRDLSLAYSPGVAEPCLEIEKDKNNAYRYTAKGNLVAVISNGTAVLGLGNIGPEASKPVMEGKGLLFKIFADIDVFDIEVDTEDVDAFIETVKNIAPTFGGINLEDIKAPEAFEIERRLKEELDIPVMHDDQHGTAIISAAALINALELAKKNIEDVKIVISGAGAAAISCSRLYQSCGAKRENMVMLDSKGVIRDDRDNLTSQKAEFATHRKIDTLEEAMIDADVFIGLSMADIVTPEMLKTMAKDPIVFAMANPNPEIKYQLAVDTRDDIIMATGRSDHPNQVNNVLGFPFIFRGALDVRASKINEEMKIAAVKALAALAKEPVPEQVNVAYEQTRLAFGRKYIIPKPFDPRLIAEIPPAVAKAAMESGVAKESITDWEKYKNSLRERLGSDNKLVRLLLSRAKLNPKRVVYAEADQLAVLKAAQIAHEEGIAIPILLGRKETIETLMKEIDFEADISIIDPKTEEENERKNRYAKVYWEQRKRRGVTYYAAQRLMRERNYFAAMMVNEGDADALISGYSRNYPSVVKPMLELIGMAKGATRIATTNVMMTKRGPMFLSDTSINIDPSAKDLAKIAVMTSKVIKTFGFEPVIAMTSYSNFGSSDNERASKVREAVSMLHRHYPELVVDGELQTDFALNDQMLRDQFPFSKLVGRKVNSLIFPNLDAANITYKLLKELNEADSIGPIMMGMKKPVHILQLDASVDEIVNMTAVAVIDAQNKEMWELEKDIS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FOFN01000001
EMBL· GenBank· DDBJ
SEP74443.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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