A0A1G5AU20 · A0A1G5AU20_9FIRM
- ProteintRNA (guanine-N(1)-)-methyltransferase
- GenetrmD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids271 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically methylates guanosine-37 in various tRNAs.
Catalytic activity
- guanosine37 in tRNA + S-adenosyl-L-methionine = N1-methylguanosine37 in tRNA + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 118 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 138-143 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | tRNA (guanine(37)-N1)-methyltransferase activity | |
Biological Process | tRNA N1-guanine methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA (guanine-N(1)-)-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Butyrivibrio
Accessions
- Primary accessionA0A1G5AU20
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 23-226 | tRNA methyltransferase TRMD/TRM10-type | |||
Compositional bias | 225-239 | Basic and acidic residues | |||
Region | 225-271 | Disordered | |||
Compositional bias | 250-271 | Basic and acidic residues | |||
Sequence similarities
Belongs to the RNA methyltransferase TrmD family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length271
- Mass (Da)30,932
- Last updated2017-11-22 v1
- Checksum2E3F91BC8B47A233
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 225-239 | Basic and acidic residues | |||
Compositional bias | 250-271 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FMVS01000002 EMBL· GenBank· DDBJ | SCX81373.1 EMBL· GenBank· DDBJ | Genomic DNA |