A0A1G3Z3J0 · A0A1G3Z3J0_9BACT

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 2 [4Fe-4S] clusters per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site68[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site71[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site74[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site78[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site113[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site116[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site119[4Fe-4S] cluster 2 (UniProtKB | ChEBI)
Binding site123[4Fe-4S] cluster 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological Processaerobic respiration

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit I
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit I
    • NDH-1 subunit I

Gene names

    • Name
      nuoI
    • ORF names
      A2007_02165

Organism names

Accessions

  • Primary accession
    A0A1G3Z3J0

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain56-884Fe-4S ferredoxin-type
Domain104-1334Fe-4S ferredoxin-type

Sequence similarities

Belongs to the complex I 23 kDa subunit family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    168
  • Mass (Da)
    19,503
  • Last updated
    2017-01-18 v1
  • Checksum
    E827F79714B5871E
MTKLVERKSLSRWEKWYLPQILHGLTITFVHFFKRKVTIQYPEERPVIPDGYRGVPTLIKDSEGREKCVACQLCEFSCPSKAIRVVPGPISTDSPFQKVEKAPKEFEINMLRCIYCGVCESACPEQAIVLQKRYSLTSYSRKELIFNKDKLYAMGGTLPDKYNKWKNK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MIDO01000103
EMBL· GenBank· DDBJ
OHE71461.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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