A0A1G3Z2H6 · A0A1G3Z2H6_9BACT
- ProteinDNA-directed RNA polymerase subunit beta'
- GenerpoC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1386 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity
- RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 71 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 73 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 86 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 89 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 462 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 464 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 466 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | DNA-directed RNA polymerase complex | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed 5'-3' RNA polymerase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | zinc ion binding | |
Biological Process | DNA-templated transcription |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA-directed RNA polymerase subunit beta'
- EC number
- Short namesRNAP subunit beta'
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Verrucomicrobiota
Accessions
- Primary accessionA0A1G3Z2H6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Interaction
Subunit
The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 237-516 | RNA polymerase N-terminal | |||
Region | 1365-1386 | Disordered | |||
Compositional bias | 1368-1386 | Polar residues | |||
Sequence similarities
Belongs to the RNA polymerase beta' chain family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,386
- Mass (Da)152,998
- Last updated2017-01-18 v1
- Checksum6F73DD8413538F50
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1368-1386 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MIDO01000115 EMBL· GenBank· DDBJ | OHE71096.1 EMBL· GenBank· DDBJ | Genomic DNA |