A0A1G3Z2H6 · A0A1G3Z2H6_9BACT

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site71Zn2+ 1 (UniProtKB | ChEBI)
Binding site73Zn2+ 1 (UniProtKB | ChEBI)
Binding site86Zn2+ 1 (UniProtKB | ChEBI)
Binding site89Zn2+ 1 (UniProtKB | ChEBI)
Binding site462Mg2+ (UniProtKB | ChEBI)
Binding site464Mg2+ (UniProtKB | ChEBI)
Binding site466Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionmagnesium ion binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta'
  • EC number
  • Short names
    RNAP subunit beta'
  • Alternative names
    • RNA polymerase subunit beta'
    • Transcriptase subunit beta'

Gene names

    • Name
      rpoC
    • ORF names
      A2007_00700

Organism names

Accessions

  • Primary accession
    A0A1G3Z2H6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain237-516RNA polymerase N-terminal
Region1365-1386Disordered
Compositional bias1368-1386Polar residues

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,386
  • Mass (Da)
    152,998
  • Last updated
    2017-01-18 v1
  • Checksum
    6F73DD8413538F50
MSTQEVRDILGFDQEQVFDYVGIAIAAPDVMRSWSKGEVKNPETINYRTFKPEPGGLFCQRIFGPVRDYECACGKYKRIKYKGVVCDRCGVEVTVSRVRRDRMGHIELAVPISHIWFLKSMPSRVGLLLDMTARDLEKVIYYENYIVIDPGKTPLEKKALLSEQEFLQLQEEYGDDAFFAKMGAEAIRILLAELDLAQMVQEIEEEIHSSRSKQSKKKLAKRLKIISGFLNSGTRPEWMVLEVLPVIPPDLRPLVPLEGGRFATSDLNDLYRRVINRNNRLKNLLQLKTPDVIINNEKRMLQESVDALFDNGRHGRPVTAAGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVIGPELRLHQCGLPKKMALVLFEPFIIRRLKELGFVHTVRGARKMIENKSPEVWDILEEVTKGHPVLLNRAPTLHRLSIQAFEPQLIEGDAIRLHPLVCSAYNADFDGDQMAVHVPLSLEAILESKLLMLASNNIFSPSSGKPVLTPSQDIVLGSYYLTVEPRRKPSEGERVPLLQSTREALAAEVEGMLSKHQWVDFVNPDFGRKTIFGNAAKKIIRTTVGRVIYNSIWPKSLGFVNGPVAKSKLGDMILNLYKIASTKQEAVDTLDRLKEMGFKIATKAGISIGIGDMIIPTEKSGIVNKSRKRLEEVDSQYQKGIITEGERTNKVIDIWSSATDEIAKATFACLESNEGKEGINPVFLMMDSGARGNRQQVRQLCGARGLMAKPSGEIIERPILSSFREGLSVLEYFVSTHGTRKGLADTALKTADAGYMTRKLCDVAMDCIISSLDDGNRDGVWKHAIYEGDDEVVKLSDRIVGRCSSEDVYSPLNPDEILVKSGEILTPEVAEKIEDLGIDRVKIMSPLTHLKRGGLSAKAYGIDPATNKLVEMGTAVGIIAAQSIGEPGTQLTMRTFHVGGVASQVLKNPEIRVRHNGQIKFKGLRLVQTADGASIVLNKTGSVIIMDKEDHELESYHIVAGAVLMVADGSEIHKGDVLAMWDPHNIPILSEKGGSVGFKDMIPGVTVKRELDESTGRIATVVIEHKEDLNPTVEVKALAGNKEGLSTGKVIATYAIPVGAQVVVHEGDEISPGALLAKTPRSASKTQDITGGLPRVAELFEARRPKDAAEMAKIDGIVSMGSTVRGKRRLIVSDTETGQQEDHLISHGRQIIVHVGDFVTKGQSLTEGAADPHEILEILGPYAVQEYLISEIQKVYRLQGVVINDKHIELIVARMLRKVRVTDPGDSDFFWGEQIDRTAFIESNERIVEAGGQPGEGEPILLGVTKASLETDSFISAASFQETTRVLTEASTLGKVDKLSGFKENVIMGQLIPAGTGFHKYRRLKVVPMGNESVEPTDRSSQGKSVELATIE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1368-1386Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MIDO01000115
EMBL· GenBank· DDBJ
OHE71096.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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