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A0A1C7MA88 · A0A1C7MA88_GRIFR

Function

function

DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, dna binding.

Type
IDPosition(s)Description
Binding site185-192ATP (UniProtKB | ChEBI)
DNA binding576-595

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleus
Molecular Function5'-3' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Biological ProcessDNA recombination
Biological ProcessDNA repair
Biological Processmitochondrial genome maintenance
Biological Processtelomere maintenance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase PIF1
  • EC number
  • Alternative names
    • DNA repair and recombination helicase PIF1

Gene names

    • Name
      pif1_6
    • Synonyms
      PIF1
    • ORF names
      A0H81_06128

Organism names

Accessions

  • Primary accession
    A0A1C7MA88

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-38Polar residues
Region1-54Disordered
Region80-137Disordered
Domain177-335AAA+ ATPase
Region477-500Disordered
Compositional bias484-498Basic and acidic residues

Sequence similarities

Belongs to the helicase family. PIF1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    600
  • Mass (Da)
    65,799
  • Last updated
    2016-11-30 v1
  • MD5 Checksum
    5E43F33783D6AA98C1E7809871455DA9
MAPSSKQPMSGLRTVKRDFSSSSIPTASQESASTDADAIPWSATPPKKKLTGLEQRLKDIQDALNGQIVSSEKVLASKPFASQLQPPMQKRPSSSQDPPAKRRQLPSSWNDPAAYNSRPAYPTASSAGNFGSTRQANRAYQPPPLIVAADSKNGAVSKPAPVFLSQEQTHILKLVQERQSLFYTGSAGTGKSVLLREIIKTLRRKHSKSPDAVAVTASTGIAACNIGGVTIHSFAGIGLGIESAEQLVSKIKKNKKASARWLRTQVLIIDEVSMVEGDLFDKLARIGSMMRKKVEPFGGIQVIVTGDFFQLPPVMKGSGNVKFAFEADMWSQTIKKTFNLTKVFRQRDPEFVDMLNEMRFGRLSEKSSQKFKDLSREIIYEDGLGATELFPRREDVERSNAVRMSVISTEEKVYLASDGGMITDQQHRDKMLANFMAPQRLALKLGAQVMLIKNMDETLVNGTMGKIVDFVDPSAAPVADDDHSGVKPGSKGPKETKKASSGIRWPLVEFLQPGGGRRRVMVQPETWKVELPNGEVQVSRTQMPLILAWAMSIHKSQGQTLERVKVDLAKVFEKGQAYVALSRATSLDGLQVLNFDPTKV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-38Polar residues
Compositional bias484-498Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LUGG01000006
EMBL· GenBank· DDBJ
OBZ73732.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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