A0A1C7MA88 · A0A1C7MA88_GRIFR
- ProteinATP-dependent DNA helicase PIF1
- Genepif1_6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids600 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Cofactor
Features
Showing features for binding site, dna binding.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 185-192 | ATP (UniProtKB | ChEBI) | |||
DNA binding | 576-595 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Molecular Function | 5'-3' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair | |
Biological Process | mitochondrial genome maintenance | |
Biological Process | telomere maintenance |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase PIF1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Polyporales > Grifolaceae > Grifola
Accessions
- Primary accessionA0A1C7MA88
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-38 | Polar residues | |||
Region | 1-54 | Disordered | |||
Region | 80-137 | Disordered | |||
Domain | 177-335 | AAA+ ATPase | |||
Region | 477-500 | Disordered | |||
Compositional bias | 484-498 | Basic and acidic residues | |||
Sequence similarities
Belongs to the helicase family. PIF1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length600
- Mass (Da)65,799
- Last updated2016-11-30 v1
- MD5 Checksum5E43F33783D6AA98C1E7809871455DA9
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-38 | Polar residues | |||
Compositional bias | 484-498 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LUGG01000006 EMBL· GenBank· DDBJ | OBZ73732.1 EMBL· GenBank· DDBJ | Genomic DNA |