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A0A174IPS4 · A0A174IPS4_9FIRM

  • Protein
    Adenosylcobinamide-GDP ribazoletransferase
  • Gene
    cobS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenosylcobinamide-GDP ribazoletransferase activity
Molecular Functioncobalamin 5'-phosphate synthase activity
Biological Processcobalamin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylcobinamide-GDP ribazoletransferase
  • EC number
  • Alternative names
    • Cobalamin synthase
    • Cobalamin-5'-phosphate synthase

Gene names

    • Name
      cobS
    • ORF names
      ERS852497_01112

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 2789STDY5834884
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Agathobacter

Accessions

  • Primary accession
    A0A174IPS4

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane31-50Helical
Transmembrane62-81Helical
Transmembrane109-129Helical
Transmembrane136-158Helical
Transmembrane178-196Helical
Transmembrane201-217Helical
Transmembrane232-253Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the CobS family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    254
  • Mass (Da)
    28,178
  • Last updated
    2016-09-07 v1
  • MD5 Checksum
    38813F96DD04ED514F0964EB343E52F2
MKLIRSCIVSFSMYSKIPMPQFKWNDDDMKYMLVFFPWIGAVIGLLLMLWRYIYSHFGVEDICYVCIGTLIPIAVTGGFHIDGFMDTMDAFHSYKPREEKLAILKDSHIGAFAVIMLAAYGLLFMGAFSQIINDKALIVFCAGFFISRCLSGIAVVSFKSAKSDGLLFMFADTAHRTIVRAALYIQLALCMAVLFIVSLPYAVAIIIAAALSFWYYYVKTKKELGGITGDTAGYFVCICECAMAVALGGVSFII

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CZAJ01000008
EMBL· GenBank· DDBJ
CUO87547.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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