A0A165WVD8 · A0A165WVD8_9AGAM

Function

function

Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Pathway

Cofactor biosynthesis; NAD+ biosynthesis; quinolinate from L-kynurenine: step 3/3.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site46O2 (UniProtKB | ChEBI)
Binding site50Fe cation (UniProtKB | ChEBI); catalytic
Binding site56Fe cation (UniProtKB | ChEBI); catalytic
Binding site56substrate
Binding site94Fe cation (UniProtKB | ChEBI); catalytic
Binding site98substrate
Binding site108substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-hydroxyanthranilate 3,4-dioxygenase activity
Molecular Functionferrous iron binding
Biological Process'de novo' NAD biosynthetic process from tryptophan
Biological Processanthranilate metabolic process
Biological Processquinolinate biosynthetic process
Biological Processtryptophan catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-hydroxyanthranilate 3,4-dioxygenase
  • EC number
  • Alternative names
    • 3-hydroxyanthranilate oxygenase
      (3-HAO
      )
    • 3-hydroxyanthranilic acid dioxygenase
      (HAD
      )
    • Biosynthesis of nicotinic acid protein 1

Gene names

    • Name
      BNA1
    • ORF names
      FIBSPDRAFT_914367

Organism names

  • Taxonomic identifier
  • Strain
    • CBS 109695
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Atheliales > Atheliaceae > Fibularhizoctonia

Accessions

  • Primary accession
    A0A165WVD8

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the 3-HAO family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    162
  • Mass (Da)
    18,581
  • Last updated
    2016-07-06 v1
  • Checksum
    31625168EF3BBD33
MPLPPPINLPLWLSENGHPLQPPVNNFCLYRGADYIVMAVGRPNERNDYHVNETEEWFYQYKSGMLLRVVNDGAFRDIRIEGGPMFLLPANTPHNPVRFADTIGLVVERIRPEESIDRLLIIREDSVHITDLGAQLKPIIQNWQNSEDARRCRECGQVAPPK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KV417735
EMBL· GenBank· DDBJ
KZP07945.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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