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A0A101DF18 · A0A101DF18_ARCFL

Function

function

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for active site.

162050100150200250300350400450500550600
TypeIDPosition(s)Description
Active site509
Active site552

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent peptidase activity
Molecular Functionserine-type endopeptidase activity
Biological Processprotein catabolic process
Biological Processproteolysis
Biological Processregulation of DNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Archaeal Lon protease
  • EC number
  • Alternative names
    • ATP-dependent protease La homolog

Gene names

    • ORF names
      XD40_0433
      , XD48_1385

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • 49_2300
    • 49_95
  • Taxonomic lineage
    Archaea > Euryarchaeota > Archaeoglobi > Archaeoglobales > Archaeoglobaceae > Archaeoglobus

Accessions

  • Primary accession
    A0A101DF18

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane118-136Helical

Keywords

Interaction

Subunit

Homohexamer. Organized in a ring with a central cavity.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain134-321Sigma-54 factor interaction
Domain423-602Lon proteolytic

Sequence similarities

Belongs to the peptidase S16 family. Archaeal LonB subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    620
  • Mass (Da)
    67,968
  • Last updated
    2016-04-13 v1
  • MD5 Checksum
    2E283F6A48DF839C95098EA3FCA22712
MNEEVREILGGLDFESTKDVAVPERLIDQVIGQDHAVEAIKKAAVQKRHVMLIGSPGTGKSMLAKAMAELLPKEELEDILVYPNPQDPNQPKIRLVPAGKGREIVEAYKEEAMKKAQARNFLIFTLVFLVIGYTVLTNPGNLIWGIIAAVLILMMSRYFIPREDRNVPKLLVDNSDKVTAPFEDATGAHAGALFGDVRHDPFQSGGLETPAHERVEAGAIHRAHKGVLYIDEINTLTIESQQKLLTALQDKKFPITGQSERSSGATVRTEPVPCDFILVAAGNLDALMGMHPALRSRIEGYGYEVYMNDTMPDTAENRAKLVRFVAQEVVKDGKIPHFDKYAVAEIIKEARRRAGRRNHLTLRLRELGGLVRTAGDIAKSEGSDIVRLEHVLKAKKIAKTIEEQLADKYLERRKDYKLFITEGFEVGRVNGLAVIGESAGIVLPIIAEVTPSMSKSEGRVIATGRLQEIAREAVMNVSAIIKKYTGKDISNMDVHIQFVGTYEGVEGDSASISIATAVISAMEGIPVDQSVAMTGSLSVKGEVLPVGGVTQKIEAAVQAGLRKVIIPKDNIDDVLLDAEHEGKIEVIPVSRIDEVLVHVLEDGKKKERLMGKFRELEIAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LGEQ01000005
EMBL· GenBank· DDBJ
KUJ94339.1
EMBL· GenBank· DDBJ
Genomic DNA
LGEX01000038
EMBL· GenBank· DDBJ
KUK06361.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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