A0A0R2P3F1 · A0A0R2P3F1_9ACTN
- ProteinTranscription termination factor Rho
- Generho
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids536 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 275-280 | ATP (UniProtKB | ChEBI) | |||
Binding site | 287-292 | ATP (UniProtKB | ChEBI) | |||
Binding site | 318 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATP-dependent activity, acting on RNA | |
Molecular Function | helicase activity | |
Molecular Function | RNA binding | |
Biological Process | DNA-templated transcription termination |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTranscription termination factor Rho
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Actinomycetes incertae sedis > ac1 cluster
Accessions
- Primary accessionA0A0R2P3F1
Proteomes
Interaction
Subunit
Homohexamer. The homohexamer assembles into an open ring structure.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 54-146 | Disordered | |||
Compositional bias | 55-81 | Basic and acidic residues | |||
Compositional bias | 82-97 | Acidic residues | |||
Compositional bias | 98-114 | Polar residues | |||
Compositional bias | 115-146 | Basic and acidic residues | |||
Domain | 157-232 | Rho RNA-BD | |||
Sequence similarities
Belongs to the Rho family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length536
- Mass (Da)59,423
- Last updated2016-01-20 v1
- Checksum324FB422588B8987
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 55-81 | Basic and acidic residues | |||
Compositional bias | 82-97 | Acidic residues | |||
Compositional bias | 98-114 | Polar residues | |||
Compositional bias | 115-146 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LIAW01000077 EMBL· GenBank· DDBJ | KRO32598.1 EMBL· GenBank· DDBJ | Genomic DNA |