A0A0R0MAQ0 · A0A0R0MAQ0_9BURK

  • Protein
    Uroporphyrinogen decarboxylase
  • Gene
    hemE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site31-35substrate
Binding site81substrate
Site81Transition state stabilizer
Binding site157substrate
Binding site212substrate
Binding site339substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionuroporphyrinogen decarboxylase activity
Biological Processprotoporphyrinogen IX biosynthetic process from glutamate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uroporphyrinogen decarboxylase
  • EC number
  • Short names
    UPD
    ; URO-D

Gene names

    • Name
      hemE
    • ORF names
      AO057_04890

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • PAE-UM
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Curvibacter

Accessions

  • Primary accession
    A0A0R0MAQ0

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain26-35Uroporphyrinogen decarboxylase (URO-D)
Domain145-161Uroporphyrinogen decarboxylase (URO-D)

Sequence similarities

Belongs to the uroporphyrinogen decarboxylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    366
  • Mass (Da)
    39,667
  • Last updated
    2016-01-20 v1
  • Checksum
    1B327AC12DBA58B0
MSSSYAPLQNDTFLRACLRQATDYTPLWLMRQAGRYLPEYCATRAKAGSFMGLATNVDYATEVTLQPLARYPLDAAILFSDILTVPDAMGLGLSFAQGEGPRFATPVRDEAAVAKLAVPDLDKLRYVFDAVTSIRKALNGRVPLIGFSGSPWTLACYMVEGAGSDDYRLVKSMLYSRPDLMHRILQVNADAVAAYLNAQIDAGAQAVMVFDSWGGVLADGAFQEFSLAYTARVLAGLKRNGVDGKIVPRIVFTKGGGLWLEQMGQLDCEVLGLDWTMNLGKARTLVGGSKALQGNIDPNVLFAPPAAIETEVKRVLESFGAPHRDPKSSGPTHIFNLGHGISQYTPPDHVSALVEAVHTHSRRMRA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LKCX01000031
EMBL· GenBank· DDBJ
KRH98822.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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