A0A0R0MAQ0 · A0A0R0MAQ0_9BURK
- ProteinUroporphyrinogen decarboxylase
- GenehemE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids366 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Catalytic activity
- uroporphyrinogen III + 4 H+ = coproporphyrinogen III + 4 CO2
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 31-35 | substrate | |||
Binding site | 81 | substrate | |||
Site | 81 | Transition state stabilizer | |||
Binding site | 157 | substrate | |||
Binding site | 212 | substrate | |||
Binding site | 339 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | uroporphyrinogen decarboxylase activity | |
Biological Process | protoporphyrinogen IX biosynthetic process from glutamate |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUroporphyrinogen decarboxylase
- EC number
- Short namesUPD ; URO-D
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Curvibacter
Accessions
- Primary accessionA0A0R0MAQ0
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 26-35 | Uroporphyrinogen decarboxylase (URO-D) | |||
Domain | 145-161 | Uroporphyrinogen decarboxylase (URO-D) | |||
Sequence similarities
Belongs to the uroporphyrinogen decarboxylase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length366
- Mass (Da)39,667
- Last updated2016-01-20 v1
- Checksum1B327AC12DBA58B0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LKCX01000031 EMBL· GenBank· DDBJ | KRH98822.1 EMBL· GenBank· DDBJ | Genomic DNA |