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A0A0N7GEL5 · A0A0N7GEL5_BOVIN

  • Protein
    NADH-ubiquinone oxidoreductase chain 4
  • Gene
    ND4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological ProcessATP synthesis coupled electron transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • BT821_Mit10
    • BT825_Mit10
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0A0N7GEL5

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane5-24Helical
Transmembrane36-55Helical
Transmembrane76-92Helical
Transmembrane98-115Helical
Transmembrane127-151Helical
Transmembrane171-191Helical

Keywords

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-91NADH:ubiquinone oxidoreductase chain 4 N-terminal
Domain94-222NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    222
  • Mass (Da)
    25,312
  • Last updated
    2016-01-20 v1
  • MD5 Checksum
    E3D39F9E73074D7E5BA3263FFA82271A
KNNMIWVNSTAHSLLISFTSLLLMNQFGDNSLNFSLLFFSDSLSTPLLILTMWLLPLMLMASQHHLSKENLTRKKLFITMLISLQLFLIMTFTAMELILFYILFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLAGSLPLLVALIYIQNTVGSLNFLMLQYWVQPVHNSWSNVFMWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGG

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue222

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KP777014
EMBL· GenBank· DDBJ
ALH44142.1
EMBL· GenBank· DDBJ
Genomic DNA
KP777015
EMBL· GenBank· DDBJ
ALH44143.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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