A0A0N4VD38 · A0A0N4VD38_ENTVE
- ProteinO-acyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids470 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H+ = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2OThis reaction proceeds in the forward direction.
- 1,2-di-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 1,3-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 1-O-(9Z-octadecenyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoAThis reaction proceeds in the forward direction.
- 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoAThis reaction proceeds in the forward direction.
- 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoAThis reaction proceeds in the forward direction.
- 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoAThis reaction proceeds in the forward direction.
- 13-cis-retinol + hexadecanoyl-CoA = 13-cis-retinyl hexadecanoate + CoAThis reaction proceeds in the forward direction.
- 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoAThis reaction proceeds in the forward direction.
- all-trans-retinol + hexadecanoyl-CoA = all-trans-retinyl hexadecanoate + CoAThis reaction proceeds in the forward direction.
- hexadecan-1-ol + hexadecanoyl-CoA = hexadecanyl hexadecanoate + CoAThis reaction proceeds in the forward direction.
- hexadecane-1,2-diol + 2 hexadecanoyl-CoA = 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoAThis reaction proceeds in the forward direction.
- hexadecane-1,2-diol + hexadecanoyl-CoA = 2-hydroxyhexadecyl hexadecanoate + CoAThis reaction proceeds in the forward direction.
Pathway
Lipid metabolism; glycerolipid metabolism.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 392 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | diacylglycerol O-acyltransferase activity | |
Molecular Function | retinol O-fatty-acyltransferase activity | |
Biological Process | triglyceride biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameO-acyltransferase
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Oxyuridomorpha > Oxyuroidea > Oxyuridae > Enterobius
Accessions
- Primary accessionA0A0N4VD38
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 145-168 | Helical | |||
Transmembrane | 174-196 | Helical | |||
Transmembrane | 259-278 | Helical | |||
Transmembrane | 309-333 | Helical | |||
Transmembrane | 370-391 | Helical | |||
Transmembrane | 403-421 | Helical | |||
Transmembrane | 433-451 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Homodimer or homotetramer; both forms have similar enzymatic activities.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-38 | Disordered | |||
Sequence similarities
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length470
- Mass (Da)54,200
- Last updated2015-12-09 v1
- Checksum9929C2B50D9E5F35
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
UXUI01009203 EMBL· GenBank· DDBJ | VDD93240.1 EMBL· GenBank· DDBJ | Genomic DNA |