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A0A0M3RDS1 · A0A0M3RDS1_9BACI

  • Protein
    Multifunctional fusion protein
  • Gene
    msrA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site11
Active site288Nucleophile

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-methionine:thioredoxin-disulfide S-oxidoreductase activity
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Molecular Functionpeptide-methionine (S)-S-oxide reductase activity
Biological Processprotein modification process
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    Peptide methionine sulfoxide reductase MsrA
  • EC number
  • Short names
    Protein-methionine-S-oxide reductase
  • Alternative names
    • Peptide-methionine (S)-S-oxide reductase
      (Peptide Met(O) reductase
      )
  • Recommended name
    Peptide methionine sulfoxide reductase MsrB
  • EC number
  • Alternative names
    • Peptide-methionine (R)-S-oxide reductase

Gene names

    • Name
      msrA
    • Synonyms
      msrB
    • ORF names
      AM500_03620

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • FJAT-18017
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus

Accessions

  • Primary accession
    A0A0M3RDS1

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain177-299MsrB

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family.
Belongs to the MsrB Met sulfoxide reductase family.
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    315
  • Mass (Da)
    36,263
  • Last updated
    2015-12-09 v1
  • MD5 Checksum
    40D1DF9B0EDDB6443813BA5FE74D90A6
MAELATFAGGCFWCMVQPFDEQPGIEKVVSGYTGGHKENPTYEEVCSDTTGHYEAVQITFDPDVFPYKKLLELYWQQIDPTDPGGQFNDRGLSYRTAIFYHSEEQRQLAEQSKQELAASGKFSKPIVTEILPAKTFYPAEEKHQDYYKKNSFHYNMYKEGSGRAPFIRATWKKKKSDEELRETLTPMQYEVTQNNGTEPPFRNEFWDLEEDGIYVDVVSGEPLFSSTDKYDAGCGWPSFTKPIKRTEIEEKLDTSYGMRRIEVRSKTADSHLGHVFDDGPGPDHARYCINSAALRFVPKDKLEEEGYGEFRKLFE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP012602
EMBL· GenBank· DDBJ
ALC88986.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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