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A0A0K2W8E3 · A0A0K2W8E3_GOUCR

  • Protein
    NADH-ubiquinone oxidoreductase chain 4
  • Gene
    nad4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      nad4

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Columbimorphae > Columbiformes > Columbidae > Goura

Accessions

  • Primary accession
    A0A0K2W8E3

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane61-82Helical
Transmembrane94-110Helical
Transmembrane116-133Helical
Transmembrane145-169Helical
Transmembrane189-212Helical
Transmembrane224-244Helical
Transmembrane256-277Helical
Transmembrane284-303Helical
Transmembrane309-329Helical
Transmembrane341-361Helical
Transmembrane381-412Helical
Transmembrane433-449Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-109NADH:ubiquinone oxidoreductase chain 4 N-terminal
Domain112-403NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    460
  • Mass (Da)
    51,285
  • Last updated
    2015-11-11 v1
  • MD5 Checksum
    E26C010A2149385F8C11BB6D374F9E7F
MLKIILPTIMLLPTALLSPQKFLWTNTTMHGLLIATLSLQWLLPTYHPHKSLTPWTGIDQISSPLLVLSCWLLPLMIIASQNHLQHEPLTRKRIFILALITIQPFIILAFSSTELMLFYISFEATLIPTLILITRWGSQPERLSAGIYLLFYTLMSSLPLLVTILYLHMQIGTLHLTMLKLTHPILDNSWTNLLSSLALLMAFMVKAPLYGLHLWLPKAHVEAPIAGSMLLAALLLKLGGYGIMRVTLLMSPLSGLLHYPFITLALWGALMTSSICLRQTDLKSLIAYSSVSHMGLVIAASMIQTHWAFSGAMILMISHGLTSSMLFCLANTNYERTHSRILILTRGLQPLLPLMATWWLLANLTNMALPPTTNLMAELTIMVALFNWSTPTIILTGTATLLTASYTLFMLLMTQRGTLPTHITSIQNSTTREHLLMALHIIPMLLLILKPDLISGTLSC

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LN589994
EMBL· GenBank· DDBJ
CEF52463.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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