A0A0G1N978 · A0A0G1N978_9BACT
- ProteinUDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
- GenemurG
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids374 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
Catalytic activity
- di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H+
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 203 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | |||
Binding site | 306 | UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity | |
Molecular Function | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | lipid glycosylation | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Candidatus Woesebacteria
Accessions
- Primary accessionA0A0G1N978
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 80-103 | Helical | |||
Transmembrane | 109-134 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 15-156 | Glycosyltransferase family 28 N-terminal | |||
Domain | 197-352 | Glycosyl transferase family 28 C-terminal | |||
Sequence similarities
Belongs to the glycosyltransferase 28 family. MurG subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length374
- Mass (Da)41,084
- Last updated2015-07-22 v1
- ChecksumD34B414E46CC1C6C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LCLM01000016 EMBL· GenBank· DDBJ | KKU17099.1 EMBL· GenBank· DDBJ | Genomic DNA |