A0A0D6PAT9 · A0A0D6PAT9_9PROT

Function

function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N2-acetylornithine and glutamate.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N2-acetyl-L-ornithine (cyclic): step 1/1.
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 1/4.

Features

Showing features for site, binding site, active site.

Type
IDPosition(s)Description
Site122Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Site123Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Binding site159substrate
Binding site185substrate
Site195-196Cleavage; by autolysis
Active site196Nucleophile
Binding site196substrate
Binding site278substrate
Binding site401substrate
Binding site406substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionglutamate N-acetyltransferase activity
Molecular FunctionL-glutamate N-acetyltransferase activity
Biological Processarginine biosynthetic process
Biological Processornithine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Including 2 domains:

  • Recommended name
    Glutamate N-acetyltransferase
  • EC number
  • Alternative names
    • Ornithine acetyltransferase
      (OATase
      )
    • Ornithine transacetylase
  • Recommended name
    Amino-acid acetyltransferase
  • EC number
  • Alternative names
    • N-acetylglutamate synthase
      (AGSase
      )

Gene names

    • Name
      argJ
    • ORF names
      Aam_010_048

Organism names

Accessions

  • Primary accession
    A0A0D6PAT9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50233963631-195Arginine biosynthesis bifunctional protein ArgJ alpha chain
ChainPRO_5023396364196-406Arginine biosynthesis bifunctional protein ArgJ beta chain

Keywords

Interaction

Subunit

Heterotetramer of two alpha and two beta chains.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the ArgJ family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    406
  • Mass (Da)
    41,713
  • Last updated
    2015-05-27 v1
  • Checksum
    FCEDED7AC36D3882
MAGQLPVSPLALPMPELPPIAGVRLATAEAGIRYKGRTDVLLAELAAGTAVAGVFTRNLCPGAPVTWCRQVLPGGLARGLVVNAGNANVFNGAVGVRAVETTAQAAATTLGTAPEQIFLASTGVIGEPLPAERIVAVMDGLKASLKQDRFAEAAKAIMTTDTFPKGATRTVELGGKTVRINGIAKGSGMIAPDMATMLCFIFTDAAIPASALQDMLAGGVERTFNCVTIDSDTSTSDTVLLFATGQAGNDLNADLTGFREALHQVLHELALLVVRDGEGAQKFVTINVQGAVSDASAKKIGLAIANSPLVKTAIAGEDANWGRIVMAVGKAGEPADRDTLGVAVGGVWMARAGGVVPGYDEAPVVAHMKGRKIEITVDIGLGEGKATVWTCDLTHGYIDINGSYRS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BANC01000010
EMBL· GenBank· DDBJ
GAN78870.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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