W9VSZ0 · W9VSZ0_9EURO

  • Protein
    Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular Functionhistone binding
Molecular Functionnucleosome binding

Names & Taxonomy

Protein names

  • Recommended name
    Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein

Gene names

    • ORF names
      A1O7_06112

Organism names

  • Taxonomic identifier
  • Strain
    • CBS 114405
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Chaetothyriomycetidae > Chaetothyriales > Herpotrichiellaceae > Cladophialophora

Accessions

  • Primary accession
    W9VSZ0

Proteomes

Organism-specific databases

Subcellular Location

Interaction

Subunit

Interacts with histones H3 and H4.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region54-85Disordered
Compositional bias65-80Polar residues
Domain244-345Histone chaperone RTT106/FACT complex subunit SPT16-like middle
Region347-532Disordered
Compositional bias373-387Basic and acidic residues
Compositional bias388-424Acidic residues
Compositional bias425-447Basic and acidic residues
Compositional bias448-478Acidic residues
Compositional bias479-498Basic and acidic residues

Sequence similarities

Belongs to the RTT106 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    532
  • Mass (Da)
    58,574
  • Last updated
    2014-05-14 v1
  • Checksum
    0D6E2D097D071E20
MSDRDTIDRAFARNSPLRKRVYEAIDATPQYAPLFEDIANYHLTSVYDRGAIDDDPASKRRKLPNGGATATTTTTLPITPAHKDQPREVVLEARDISFSLPQRKKLHLGMAQYGTDINVAGTSFAIFTRNPATNEVDMEVPFSRFAYALRLPVPEKAAKQYNFVLIPRPGTTGVEPIIWTVNAGPLKSCTIPNEQLAIVAAGPDDVLECALGFVLRQSNVSLSLPSPDEFYSATPESHRKGDKAYHVKAHRGSKDGYLFFLSNGIFFGFKKPLAFFAFEDIESISYTSVLQRTFNLNIAHRPSGSGEADDNANAIQEVEFSMLDQADFVGIDEYVKRHGLQDASLAEARRAKKSATNAKPGGIQNGDPAGEGEGEDPDTRTELEKAQQQLDDEEDEDEEDYDPGSDGESEGSGSSDDDDDDDDREYERERKKSKGKDLVKEELGSEAEDVSVTEDEDEGEGEGEAENGDELEDEGDKEEQPGANDRDRHDRTPGKRDPNARRGGPTIASIPSHDGGWTYQEGMPDPDDEDQL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias65-80Polar residues
Compositional bias373-387Basic and acidic residues
Compositional bias388-424Acidic residues
Compositional bias425-447Basic and acidic residues
Compositional bias448-478Acidic residues
Compositional bias479-498Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AMGW01000004
EMBL· GenBank· DDBJ
EXJ58683.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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