V9N1W9 · V9N1W9_9ANNE

  • Protein
    NADH-ubiquinone oxidoreductase chain 2
  • Gene
    ND2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological Processmitochondrial electron transport, NADH to ubiquinone

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 2
  • EC number

Gene names

    • Name
      ND2

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • 10F
    • 11F
    • 12F
    • 13F
    • 14F
  • Taxonomic lineage
    Eukaryota > Metazoa > Spiralia > Lophotrochozoa > Annelida > Clitellata > Oligochaeta > Crassiclitellata > Lumbricina > Glossoscolecidae > Pontoscolex

Accessions

  • Primary accession
    V9N1W9

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane60-82Helical
Transmembrane88-113Helical
Transmembrane169-189Helical
Transmembrane210-228Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-234NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    238
  • Mass (Da)
    26,295
  • Last updated
    2014-03-19 v1
  • Checksum
    701E55CBBD66BA93
FLWVSMELNLLSFVPIMMMSKSNQEIEGSIKYFLAQATGSAILLFSSSMMWVVQTWTPNFFIPLLTFSILLKLGGAPCHFWYPSVMSSISWVSCLILSTWQKVAPISILAFLIPTQNNTTHILAGLNAITGGIMGMNQNSVRSIMAFSSIGQMGWMMSLMAIHKPAASILYFMIYATLILPLFLMFNALNTKTIKSLNKLASKSTLIQSSISLLLLSIAGLPPLTGFFPKLMTVFLLT

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue238

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KC665795
EMBL· GenBank· DDBJ
AGJ50216.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665796
EMBL· GenBank· DDBJ
AGJ50217.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665797
EMBL· GenBank· DDBJ
AGJ50218.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665798
EMBL· GenBank· DDBJ
AGJ50219.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665799
EMBL· GenBank· DDBJ
AGJ50220.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665800
EMBL· GenBank· DDBJ
AGJ50221.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665801
EMBL· GenBank· DDBJ
AGJ50222.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665802
EMBL· GenBank· DDBJ
AGJ50223.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665803
EMBL· GenBank· DDBJ
AGJ50224.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665804
EMBL· GenBank· DDBJ
AGJ50225.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665805
EMBL· GenBank· DDBJ
AGJ50226.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665806
EMBL· GenBank· DDBJ
AGJ50227.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665807
EMBL· GenBank· DDBJ
AGJ50228.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665808
EMBL· GenBank· DDBJ
AGJ50229.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665809
EMBL· GenBank· DDBJ
AGJ50230.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665810
EMBL· GenBank· DDBJ
AGJ50231.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665812
EMBL· GenBank· DDBJ
AGJ50233.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665813
EMBL· GenBank· DDBJ
AGJ50234.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665814
EMBL· GenBank· DDBJ
AGJ50235.1
EMBL· GenBank· DDBJ
Genomic DNA
KC665835
EMBL· GenBank· DDBJ
AGJ50256.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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