V7F2S6 · V7F2S6_9HYPH

Function

function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site11substrate
Binding site11-12ATP (UniProtKB | ChEBI)
Binding site19ATP (UniProtKB | ChEBI)
Site19Transition state stabilizer
Binding site43substrate
Binding site80substrate
Binding site94substrate
Binding site95-97ATP (UniProtKB | ChEBI)
Binding site105ATP (UniProtKB | ChEBI)
Binding site130-136ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantetheine-phosphate adenylyltransferase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphopantetheine adenylyltransferase
  • EC number
  • Alternative names
    • Dephospho-CoA pyrophosphorylase
    • Pantetheine-phosphate adenylyltransferase
      (PPAT
      )

Gene names

    • Name
      coaD
    • ORF names
      X767_12180

Organism names

  • Taxonomic identifier
  • Strain
    • LSJC264A00
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Phyllobacteriaceae > Mesorhizobium

Accessions

  • Primary accession
    V7F2S6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-140Cytidyltransferase-like

Sequence similarities

Belongs to the bacterial CoaD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    166
  • Mass (Da)
    17,667
  • Last updated
    2014-02-19 v1
  • Checksum
    09A473FF9032FD42
MTDRIALYAGSFDPLTNGHLDVLKASLAVADTVYAAIGTHPGKTPLFSFDERVKLIEAATKAEFGRDGDRIKVVAFDGLVIDAARKHGASIMIRGLRDGTDLDYEMQMAGMNETMAPELQTVFLPASPSVRTITATLVRQIASMGGDIRPFVPAAVAGALTAKFAK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AYVQ01000011
EMBL· GenBank· DDBJ
ESX24377.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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