V4KBR8 · V4KBR8_EUTSA
- ProteinDNA polymerase alpha subunit B
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids622 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | alpha DNA polymerase:primase complex | |
Molecular Function | DNA binding | |
Biological Process | DNA replication initiation |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase alpha subunit B
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Eutremeae > Eutrema
Accessions
- Primary accessionV4KBR8
Proteomes
Genome annotation databases
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 5-58 | DNA polymerase alpha subunit B N-terminal | ||||
Sequence: EEIKREFNRSGFALVEEEEILERCVTLCINYSLKPSELVSSWELYHLNRQIIDQ | ||||||
Compositional bias | 107-125 | Polar residues | ||||
Sequence: TEETVTTPTNNSQRLHPDP | ||||||
Region | 107-130 | Disordered | ||||
Sequence: TEETVTTPTNNSQRLHPDPFDSIN | ||||||
Domain | 242-323 | DNA polymerase alpha subunit B OB | ||||
Sequence: EQVDPAVASQRSIFAVGMICCDGEGHLNDKSILLQSSAERTSGQRVPLDLNRLNQFSIFPGQIVGIEGQNPSGHYFTASKLV | ||||||
Domain | 363-573 | DNA polymerase alpha/delta/epsilon subunit B | ||||
Sequence: FIVASGPFTTTDNLLFEPLNELLAYAKRKPPQLLVLLGPFVDSEHPEIKKGAVDATFNEIFHVEVLRKLQDYVEFMGSEVRVVLVPSIRDANHDFIFPQPPFNIHIPDLEHQMTSLSNPGTFEANQVKVGCCTVDVLKHLSGEEMSKNPSGATTDRMSRLASHLLRQRSFYPLYPPPESLPYDSTLAPKALQISSIPDILLLPSDMRYFVK |
Sequence similarities
Belongs to the DNA polymerase alpha subunit B family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length622
- Mass (Da)69,301
- Last updated2014-01-22 v1
- Checksum36DBA3369D316195
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 107-125 | Polar residues | ||||
Sequence: TEETVTTPTNNSQRLHPDP |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KI517953 EMBL· GenBank· DDBJ | ESQ28529.1 EMBL· GenBank· DDBJ | Genomic DNA |