S0EHD0 · FUS3_GIBF5
- ProteinGlutathione S-transferase-like protein FUS3
- GeneFUS3
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids210 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Glutathione S-transferase-like protein; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:23932525).
Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (PubMed:23932525).
The other FUS cluster members are not essential for fusarin C biosynthesis (PubMed:23932525).
Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (PubMed:23932525).
The other FUS cluster members are not essential for fusarin C biosynthesis (PubMed:23932525).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | transferase activity | |
Biological Process | translational elongation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione S-transferase-like protein FUS3
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium fujikuroi species complex
Accessions
- Primary accessionS0EHD0
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Phenotypes & Variants
Disruption phenotype
Does not alter fusarin C production (PubMed:23932525).
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000437367 | 1-210 | Glutathione S-transferase-like protein FUS3 | |||
Sequence: MPNARVFKILAAAKLNNIALEIPAYQHGVTNKSAEFLLKFPAGKVPAFEGPDGFCLVESDAIAQYVAQSGPQASQLLGQDAMSSAKIRQWISFFAEEIYPTVLDLVMWRVGLGAFDETTETKALTQLVYGLSVLEKHLGTGALLVGDKLTLADLTGASTLLWAFMHIVDEPMRQQYPNVVAWYLKVVQNEEVEEVFGKPNFIEKRRLGAK |
Expression
Induction
Expressed under high amounts of nitrogen via regulation by GLN1 (PubMed:23932525).
Moreover, components of the fungal-specific velvet complex VEL1, VEL2 and LAE1 act also as positive regulators of expression (PubMed:20572938, PubMed:23932525).
Finally, expression is induced under acidic conditions in a PACC-independent manner (PubMed:23932525).
Moreover, components of the fungal-specific velvet complex VEL1, VEL2 and LAE1 act also as positive regulators of expression (PubMed:20572938, PubMed:23932525).
Finally, expression is induced under acidic conditions in a PACC-independent manner (PubMed:23932525).
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-74 | GST N-terminal | ||||
Sequence: MPNARVFKILAAAKLNNIALEIPAYQHGVTNKSAEFLLKFPAGKVPAFEGPDGFCLVESDAIAQYVAQSGPQAS | ||||||
Domain | 80-206 | GST C-terminal | ||||
Sequence: DAMSSAKIRQWISFFAEEIYPTVLDLVMWRVGLGAFDETTETKALTQLVYGLSVLEKHLGTGALLVGDKLTLADLTGASTLLWAFMHIVDEPMRQQYPNVVAWYLKVVQNEEVEEVFGKPNFIEKRR |
Sequence similarities
Belongs to the GST superfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length210
- Mass (Da)23,160
- Last updated2013-09-18 v1
- Checksum9659BA9CA2488B7D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
HF679031 EMBL· GenBank· DDBJ | CCT73262.1 EMBL· GenBank· DDBJ | Genomic DNA |