S0DQI7 · LAEA_GIBF5
- ProteinSecondary metabolism regulator LAE1
- GeneLAE1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids316 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Methyltransferase that performs automethylation (By similarity).
No other methyl-accepting substrate has been identified yet (By similarity).
Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:20572938).
Controls the expression of the gibberellins gene clusters, but does not affect bikaverin production (PubMed:20572938).
Controls the expression of the fusaric acid gene cluster (PubMed:24389666).
Acts as a virulence factors during infection, most likely through activation of gibberellins biosynthesis (PubMed:20572938).
No other methyl-accepting substrate has been identified yet (By similarity).
Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:20572938).
Controls the expression of the gibberellins gene clusters, but does not affect bikaverin production (PubMed:20572938).
Controls the expression of the fusaric acid gene cluster (PubMed:24389666).
Acts as a virulence factors during infection, most likely through activation of gibberellins biosynthesis (PubMed:20572938).
Catalytic activity
- L-methionyl-[protein] + S-adenosyl-L-methionine = S-methyl-L-methionyl-[protein] + S-adenosyl-L-homocysteineThis reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | methyltransferase activity | |
Biological Process | methylation | |
Biological Process | sporulation resulting in formation of a cellular spore |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameSecondary metabolism regulator LAE1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium fujikuroi species complex
Accessions
- Primary accessionS0DQI7
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000435749 | 1-316 | Secondary metabolism regulator LAE1 | |||
Sequence: MVVMPPQNSVNESEGRYLQDGFWQHGRFYGSWKPGKYLFPIDSEELNRLDIFHKVFLLARDNKPFLAPIRRTSPRIMDIGTGTGIWAINVAEECLSDAQIMAVDLNQIQPALIPPGFMPKQYDIEEPSWGPLLADCDLIHMRMLLGSIQTDLWPQVYHNAFEHLTPGIGFLEHIEVDWIPRCDDDERPANSAFVKWAELFLDGMDRFNRSVRVIPQEHRQMLEATGFTDVKQEVIKAYVCPWSADRNEREIARWFNIGLSHSLEAMSLKPLIEKLGFEAEDVRELCERAKRETCVLRYHTYCNIHVWTARKPGPQQ |
Expression
Induction
Expression is regulated by the VEL1 (PubMed:20572938).
Structure
Family & Domains
Sequence similarities
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length316
- Mass (Da)36,624
- Last updated2016-03-16 v2
- Checksum4657FCFE4FFDB2DA
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FN548141 EMBL· GenBank· DDBJ | CBE54370.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
HF679023 EMBL· GenBank· DDBJ | CCT62818.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. |