R6JM75 · R6JM75_9CLOT

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster per subunit.

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N1-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site233[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site280Mg2+ (UniProtKB | ChEBI)
Binding site343Mg2+ (UniProtKB | ChEBI)
Binding site344Mg2+ (UniProtKB | ChEBI)
Binding site380[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site460[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site463[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionamidophosphoribosyltransferase activity
Molecular Functioniron-sulfur cluster binding
Molecular Functionmetal ion binding
Biological Process'de novo' IMP biosynthetic process
Biological Processpurine nucleobase biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Amidophosphoribosyltransferase
  • EC number
  • Short names
    ATase
  • Alternative names
    • Glutamine phosphoribosylpyrophosphate amidotransferase

Gene names

    • ORF names
      BN539_00976

Organism names

Accessions

  • Primary accession
    R6JM75

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-218Glutamine amidotransferase type-2

Sequence similarities

In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    468
  • Mass (Da)
    51,897
  • Last updated
    2013-07-24 v1
  • Checksum
    CE83133B805B3FD1
MGGYFAAVSKEDCVFDLFFGVDYHSHLGTRRAGMAVYDPETGFDKAIHNIENAPFRTKFTKESQEMHGTMGIGCISDFEAQPILVRSHHGTFAITTVGKINNADAIVDEIIGTNAHFFEMHNGEINPTELVAALIDQKENFVEGIRYAQDVIDGSMSMLLLTPKGVYAARDKLGRTPIVLGKKPDGYCASFESFAYLNLGYTDDRELGPGEIVVLTPDGVQQLVAPGKKMKICTFLWVYYGYPSSSYQGISVEKMRYHCGELLAGRDNAKPDIVAGVPDSGIAHAIGYANASGIPFSRPFVKYTPTWPRSFMPPNQTKRNLIAKMKLIPVHDLIEGKSLLLIDDSIVRGTQLRETTEFLYASGAKEVHIRPACPPLLFGCKYLNFSRSTSEMELITRRVILELEGGDPTKEVLAEYADPDSEKYAAMVEKIGEKLHFTSLRYHRLDDMIASVGIPADQLCTYCWNGKE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CBDU010000026
EMBL· GenBank· DDBJ
CDB51077.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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