Q9GL25 · ESPB1_CANLF

Function

function

Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell surface
Cellular Componentextracellular region
Molecular Functionheparin binding
Biological Processsingle fertilization
Biological Processsperm capacitation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Epididymal sperm-binding protein 1
  • Alternative names
    • CeE12
    • E12a
    • Epididymal secretory protein 12

Gene names

    • Name
      ELSPBP1
    • Synonyms
      E12

Organism names

Accessions

  • Primary accession
    Q9GL25
  • Secondary accessions
    • Q9GL26

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-23
ChainPRO_000030824824-245Epididymal sperm-binding protein 1
Disulfide bond51↔75
Disulfide bond65↔88
Disulfide bond96↔122
Disulfide bond110↔137
Disulfide bond151↔175
Disulfide bond165↔190
Disulfide bond204↔230
Disulfide bond218↔245

Keywords

Proteomic databases

Expression

Tissue specificity

Detected in epididymal duct epithelium, cauda epididymidal fluid and on sperm membrane (at protein level).

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain46-90Fibronectin type-II 1
Domain91-139Fibronectin type-II 2
Domain146-192Fibronectin type-II 3
Domain199-245Fibronectin type-II 4

Sequence similarities

Belongs to the seminal plasma protein family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    245
  • Mass (Da)
    28,746
  • Last updated
    2001-03-01 v1
  • Checksum
    DBDF6A6B540D5010
MNPWSSYLLGWTTFLLYFYETSGKIPNLSSLGKHEFTKPWISIKEDQKDSCVFPFVYKGSSYFSCIKTNSFSPWCATRAVYNGQWKFCMADDYPRCIFPFIFRGKSHNSCITEGSFLRRLWCSVTSSFDENQQWKYCETNEYGGNSFSKPCIFPSIFRNSTIFECMEDENNKLWCPTTENMDEDGKWSLCADTRISSLVPGFPCHFPFSYKNKNYYNCIGKGTKENLTWCATSYNYDRDHTWVYC

Sequence caution

The sequence CAC14265.1 differs from that shown. Reason: Erroneous initiation

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ278477
EMBL· GenBank· DDBJ
CAC14266.1
EMBL· GenBank· DDBJ
mRNA
AJ278477
EMBL· GenBank· DDBJ
CAC14265.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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