Q9CJU0 · BIOF_PASMU
- ProteinPutative 8-amino-7-oxononanoate synthase
- GenebioF
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids387 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
Catalytic activity
- 6-carboxyhexanoyl-[ACP] + H+ + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]
Cofactor
Pathway
Cofactor biosynthesis; biotin biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 19 | substrate | ||||
Sequence: R | ||||||
Binding site | 107-108 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: GY | ||||||
Binding site | 132 | substrate | ||||
Sequence: H | ||||||
Binding site | 180 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 206-209 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: DEAH | ||||||
Binding site | 237-240 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: TFGK | ||||||
Binding site | 354 | substrate | ||||
Sequence: T |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 8-amino-7-oxononanoate synthase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | biotin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative 8-amino-7-oxononanoate synthase
- EC number
- Short namesAONS
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pasteurellales > Pasteurellaceae > Pasteurella
Accessions
- Primary accessionQ9CJU0
Proteomes
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000381060 | 1-387 | Putative 8-amino-7-oxononanoate synthase | |||
Sequence: MIRYYQQQLADLKAQNQFRQLPQLIHRGRFIQREDNTMLNMSSNDYLGLANNEALRQAFFTQYQDQLPALTSSSSRLLTGSFPIYDELESLMAQAFGRETALLFNSGYHANIGILPALADKKTLIVADKLVHASMIDGIRLAQCEFVRFRHHDYAHLEQILQKNDRTFERIIVVTESVFSMDGDCADLTQLVALKQRYPQVMLYVDEAHAIGVLGEKGLGLAEQQGCINQIDILVGTFGKALGSMGAYVICDQVIRDYLVNKMRPLIFSTALPPFNVAWTHFVFQQLPHLQAERAHLAQLSQHLRQAIVDIFQVPMPSESCIVPYILGDNELTVRTAQRLQQQGYYCLPIRPPTVPKGTSRIRFSLTADMQVAEVEQFIACLQELAE | ||||||
Modified residue | 240 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length387
- Mass (Da)43,837
- Last updated2001-06-01 v1
- Checksum692F648BB785F5AF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE004439 EMBL· GenBank· DDBJ | AAK03985.1 EMBL· GenBank· DDBJ | Genomic DNA |