Q9C0N4 · SODC_CRYGA

Function

function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Cu cation (UniProtKB | Rhea| CHEBI:23378 )

Note: Binds 1 copper ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site47Cu cation (UniProtKB | ChEBI); catalytic
Binding site49Cu cation (UniProtKB | ChEBI); catalytic
Binding site64Cu cation (UniProtKB | ChEBI); catalytic
Binding site64Zn2+ (UniProtKB | ChEBI); structural
Binding site72Zn2+ (UniProtKB | ChEBI); structural
Binding site81Zn2+ (UniProtKB | ChEBI); structural
Binding site84Zn2+ (UniProtKB | ChEBI); structural
Binding site121Cu cation (UniProtKB | ChEBI); catalytic
Binding site144substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncopper ion binding
Molecular Functionsuperoxide dismutase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Superoxide dismutase [Cu-Zn]
  • EC number

Gene names

    • Name
      SOD1

Organism names

Accessions

  • Primary accession
    Q9C0N4

Organism-specific databases

Subcellular Location

Keywords

Phenotypes & Variants

Miscellaneous

PTM/Processing

Features

Showing features for initiator methionine, chain, disulfide bond.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00001641172-154Superoxide dismutase [Cu-Zn]
Disulfide bond58↔147

Keywords

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the Cu-Zn superoxide dismutase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    154
  • Mass (Da)
    15,637
  • Last updated
    2007-01-23 v3
  • Checksum
    CA4C2B4BA8F43FE4
MVKAVAVLKGDSPVTGVITFTQEKEGAPVTVSGDIKNLDANAERGFHVHEFGDNTNGCTSAGPHFNPHGKNHGAPSDSERHVGDLGNVKTDGNGVASVNISDKSLSLFGPYSIIGRTIVVHAGTDDFGKGGNAESLKTGNAGARAACGVIGISN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF248049
EMBL· GenBank· DDBJ
AAK31918.1
EMBL· GenBank· DDBJ
mRNA
AF248050
EMBL· GenBank· DDBJ
AAK31919.1
EMBL· GenBank· DDBJ
Genomic DNA
AF248051
EMBL· GenBank· DDBJ
AAK31920.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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