Q9AEU0 · SECY2_STRGN

  • Protein
    Accessory Sec system protein translocase subunit SecY2
  • Gene
    secY2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The central subunit of a protein translocation channel (Potential). Part of the accessory SecA2/SecY2 system specifically required to export GspB, a serine-rich repeat cell wall protein encoded upstream in the same operon.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionprotein transmembrane transporter activity
Biological ProcessSRP-dependent cotranslational protein targeting to membrane, translocation

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Accessory Sec system protein translocase subunit SecY2

Gene names

    • Name
      secY2

Organism names

  • Taxonomic identifier
  • Strain
    • M99
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus

Accessions

  • Primary accession
    Q9AEU0

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane13-33Helical
Transmembrane65-85Helical
Transmembrane104-124Helical
Transmembrane133-153Helical
Transmembrane158-178Helical
Transmembrane192-212Helical
Transmembrane248-268Helical
Transmembrane287-307Helical
Transmembrane345-365Helical
Transmembrane370-390Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Loss of adherence to human platelet cells, loss of export of cell wall protein GspB; GspB accumulates in the cytoplasm.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004142081-407Accessory Sec system protein translocase subunit SecY2

Interaction

Subunit

May form heterotrimers with SecE and SecG subunits (Potential). Component of the accessory SecA2/SecY2 protein translocase complex required to export cell wall protein GspB.

Structure

Family & Domains

Sequence similarities

Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    407
  • Mass (Da)
    46,158
  • Last updated
    2001-06-01 v1
  • Checksum
    9B516E14ADEE7E16
MKSFFKPLILKKFLWTLLFVFIYVLGSKLTLPFVDVSSIAKLNGDSVTLNYAAALMGGNLRSMSFFSIGLAPWMSSILIWQMFTVSKRLGLNKLSMESQEKRRMLLTLAIALIQSLGLVLNLPLKTVAGVGQGTIVFLDTLILIAGTYFLIWLTDLNSSMGLGGSIMIVMVSMISYIPQDIWLSIQELKISPLILALIGFFSLCFLYLAVLVERAKYRIPINKINIHNRFKKYSYLDIRVNAAGGLPIMYAMTLVSIPQYFLMLLLFFQPNNRLLKEGILSLAMGGIPWFILYLLTIFILAWAFAFINVNSDQIAERMQRSGEYIENLYPGEATRRYIHKTVGYFAFVGALYLVLVAGLPMLLIFLDIRYMRLGMIPGMFMIFIGMVFSIKDEVDTLTLNDRYHSLF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY028381
EMBL· GenBank· DDBJ
AAK16997.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp