Q9A707 · ISPT_CAUVC
- ProteinIsoprenyl transferase
- GeneuppS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids259 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
Cofactor
Note: Binds 2 magnesium ions per subunit.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 30 | |||||
Sequence: D | ||||||
Binding site | 30 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 31-34 | substrate | ||||
Sequence: GNGR | ||||||
Binding site | 35 | substrate | ||||
Sequence: W | ||||||
Binding site | 43 | substrate | ||||
Sequence: R | ||||||
Binding site | 47 | substrate | ||||
Sequence: H | ||||||
Binding site | 75-77 | substrate | ||||
Sequence: STE | ||||||
Active site | 78 | Proton acceptor | ||||
Sequence: N | ||||||
Binding site | 79 | substrate | ||||
Sequence: W | ||||||
Binding site | 81 | substrate | ||||
Sequence: R | ||||||
Binding site | 198 | substrate | ||||
Sequence: R | ||||||
Binding site | 204-206 | substrate | ||||
Sequence: RIS | ||||||
Binding site | 217 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: E |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | di-trans,poly-cis-undecaprenyl-diphosphate synthase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | polyprenyltransferase activity | |
Biological Process | polyprenol biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameIsoprenyl transferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Caulobacterales > Caulobacteraceae > Caulobacter
Accessions
- Primary accessionQ9A707
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000123590 | 1-259 | Isoprenyl transferase | |||
Sequence: MPATTGPQDVSGRAGGPASTERLHVAIIMDGNGRWAKQRGMPRVLGHRAGVNALKRTVEGAQSQNVGVLTVFGFSTENWSRPPQEVSELMGLLKAYVESDLERLAKAGVRVRIIGRRTGLSPDIAEVIERAERRTAQNSEFVLQVAFNYGGQADITDAARAFAERVERGEAKASDLNEKTFEQFLSTASAPPPDLIVRTSGERRISNFLLWDCAYAELVFQDVLWPDYGPEALAAAIAEYRGRDRRYGGVAADDVAVAG |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length259
- Mass (Da)28,161
- Last updated2001-06-01 v1
- Checksum2D148C19567BCEF8
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE005673 EMBL· GenBank· DDBJ | AAK23894.1 EMBL· GenBank· DDBJ | Genomic DNA |