Q95WK4 · Q95WK4_ANOQU

Function

function

Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number

Gene names

    • Name
      G6pd

Organism names

Accessions

  • Primary accession
    Q95WK4

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-152Glucose-6-phosphate dehydrogenase NAD-binding

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    153
  • Mass (Da)
    17,901
  • Last updated
    2001-12-01 v1
  • Checksum
    48F4D50B38AC19DD
LWWLFRDNLVPSDTKFVGYARSKLSVAELKEKCRQYMKVKDAELEKFDEFWSVNFYVAGSYDSRRDFELLNQEIAKFEVGRAANRLFYLALPPSVFESVTVHIRNTCMGEKGWNRIIVEKPFGRDASSSNALSAHLSKLFSEDQLYRIDHYLV

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue153

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF317809
EMBL· GenBank· DDBJ
AAL18428.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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