Q8P1F3 · TRMD_STRP8
- ProteintRNA (guanine-N(1)-)-methyltransferase
- GenetrmD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids239 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Specifically methylates guanosine-37 in various tRNAs.
Catalytic activity
- guanosine37 in tRNA + S-adenosyl-L-methionine = N1-methylguanosine37 in tRNA + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | tRNA (guanine(37)-N1)-methyltransferase activity | |
Biological Process | tRNA N1-guanine methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA (guanine-N(1)-)-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionQ8P1F3
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000060471 | 1-239 | tRNA (guanine-N1-)-methyltransferase | |||
Sequence: MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKARHVDDEPYGGGQGMLLRAQPIFDTIEQIEVKKPRIILLDPAGKPFTQAYAEELALEEELIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTIVDATVRLIPQVLGKESSHQDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLLERYDFSEEERKLLDKIKEALG |
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length239
- Mass (Da)27,559
- Last updated2002-10-01 v1
- Checksum68AB5E74741EFF5C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE009949 EMBL· GenBank· DDBJ | AAL97558.1 EMBL· GenBank· DDBJ | Genomic DNA |