Q830P3 · MURB_ENTFA
- ProteinUDP-N-acetylenolpyruvoylglucosamine reductase
- GenemurB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids300 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation.
Catalytic activity
- NADP+ + UDP-N-acetyl-alpha-D-muramate = H+ + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine
Cofactor
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 172 | |||||
Sequence: R | ||||||
Active site | 222 | Proton donor | ||||
Sequence: S | ||||||
Active site | 292 | |||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | FAD binding | |
Molecular Function | UDP-N-acetylmuramate dehydrogenase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylenolpyruvoylglucosamine reductase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Enterococcaceae > Enterococcus
Accessions
- Primary accessionQ830P3
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000179210 | 1-300 | UDP-N-acetylenolpyruvoylglucosamine reductase | |||
Sequence: MNTKAMLETLNEITLLVDEPLKNVTFTKTGGPADVLALPKTKKEVEEIVAYCREQGLSWLVLGNASNLIVRDGGIRDVVIMLTEMKEIKVAGTTMIVDAGAKLIDTTYEALAADLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFQSAEVLLADGTIQTMTKEDLNFRYRHSEIQELHCIVLQATFALEKGNHAEIKAQMDELTELRELKQPLEYPSCGSVFKRPVGHFTGKLIQDAGLQGLKWGGAQISEKHAGFIVNIDHATATDYVELIAHIQEVIKEKFDVELQTEVRIIGEEV |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 28-193 | FAD-binding PCMH-type | ||||
Sequence: KTGGPADVLALPKTKKEVEEIVAYCREQGLSWLVLGNASNLIVRDGGIRDVVIMLTEMKEIKVAGTTMIVDAGAKLIDTTYEALAADLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFQSAEVLLADGTIQTMTKEDLNFRYRHSEIQELHCIVLQATFALEKG |
Sequence similarities
Belongs to the MurB family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length300
- Mass (Da)32,841
- Last updated2003-06-01 v1
- ChecksumF83449A51CC02090
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE016830 EMBL· GenBank· DDBJ | AAO82434.1 EMBL· GenBank· DDBJ | Genomic DNA |