Q7Y1B6 · GAI_SOLLC
- ProteinDELLA protein GAI
- GeneGAI
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids588 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway (By similarity).
Its degradation is not essential for germination
Its degradation is not essential for germination
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | sequence-specific DNA binding | |
Biological Process | gibberellic acid mediated signaling pathway | |
Biological Process | hyperosmotic salinity response | |
Biological Process | jasmonic acid mediated signaling pathway | |
Biological Process | negative regulation of gibberellic acid mediated signaling pathway | |
Biological Process | negative regulation of seed germination | |
Biological Process | regulation of DNA-templated transcription | |
Biological Process | regulation of reactive oxygen species metabolic process | |
Biological Process | regulation of seed dormancy process | |
Biological Process | response to abscisic acid | |
Biological Process | response to ethylene | |
Biological Process | salicylic acid mediated signaling pathway |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameDELLA protein GAI
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Solanales > Solanaceae > Solanoideae > Solaneae > Solanum > Solanum subgen. Lycopersicon
Accessions
- Primary accessionQ7Y1B6
Proteomes
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000132245 | 1-588 | DELLA protein GAI | |||
Sequence: MKRDRDRDREREKRAFSNGAVSSGKSKIWEEDEEEKPDAGMDELLAVLGYKVKSSDMADVAQKLEQLEMAMGTTMEDGITHLSTDTVHKNPSDMAGWVQSMLSSISTNFDMCNQENDVLVSGCGSSSSIIDFSQNHRTSTISDDDLRAIPGGAVFNSDSNKRHRSTTSSFSTTSSSMVTDSSATRPVVLVDSQETGVRLVHTLMACAEAVQQENLTLADQLVRHIGILAVSQSGAMRKVATYFAEALARRIYKIYPQDSMESSYTDVLQMHFYETCPYLKFAHFTANQAILEAFTGCNKVHVIDFSLKQGMQWPALMQALALRPGGPPAFRLTGIGPPQPDNTDALQQVGWKLAQLAETIGVEFEFRGFVANSLADLDATILDIRPSETEAVAINSVFELHRLLSRPGAIEKVLNSIKQINPKIVTLVEQEANHNAGVFIDRFNEALHYYSTMFDSLESSGSSSSASPTGILPQPPVNNQDLVMSEVYLGRQICNVVACEGSDRVERHETLNQWRVRMNSSGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENDGCLMLGWHTRPLIATSAWKLLPDSGTGAGEVEL |
Post-translational modification
Phosphorylated.
Ubiquitinated. Upon GA application it is ubiquitinated, leading to its subsequent degradation (By similarity).
Keywords
- PTM
Proteomic databases
Expression
Tissue specificity
Expressed in both vegetative and reproductive tissues.
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, motif, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-16 | Basic and acidic residues | ||||
Sequence: MKRDRDRDREREKRAF | ||||||
Region | 1-38 | Disordered | ||||
Sequence: MKRDRDRDREREKRAFSNGAVSSGKSKIWEEDEEEKPD | ||||||
Motif | 42-46 | DELLA motif | ||||
Sequence: DELLA | ||||||
Region | 152-177 | Disordered | ||||
Sequence: GAVFNSDSNKRHRSTTSSFSTTSSSM | ||||||
Compositional bias | 158-177 | Polar residues | ||||
Sequence: DSNKRHRSTTSSFSTTSSSM | ||||||
Domain | 190-574 | GRAS | ||||
Sequence: VDSQETGVRLVHTLMACAEAVQQENLTLADQLVRHIGILAVSQSGAMRKVATYFAEALARRIYKIYPQDSMESSYTDVLQMHFYETCPYLKFAHFTANQAILEAFTGCNKVHVIDFSLKQGMQWPALMQALALRPGGPPAFRLTGIGPPQPDNTDALQQVGWKLAQLAETIGVEFEFRGFVANSLADLDATILDIRPSETEAVAINSVFELHRLLSRPGAIEKVLNSIKQINPKIVTLVEQEANHNAGVFIDRFNEALHYYSTMFDSLESSGSSSSASPTGILPQPPVNNQDLVMSEVYLGRQICNVVACEGSDRVERHETLNQWRVRMNSSGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENDGCLMLGWHTRPLIATSAWK | ||||||
Region | 197-251 | Leucine repeat I (LRI) | ||||
Sequence: VRLVHTLMACAEAVQQENLTLADQLVRHIGILAVSQSGAMRKVATYFAEALARRI | ||||||
Region | 269-334 | VHIID | ||||
Sequence: QMHFYETCPYLKFAHFTANQAILEAFTGCNKVHVIDFSLKQGMQWPALMQALALRPGGPPAFRLTG | ||||||
Motif | 300-304 | VHIID | ||||
Sequence: VHVID | ||||||
Region | 348-380 | Leucine repeat II (LRII) | ||||
Sequence: QVGWKLAQLAETIGVEFEFRGFVANSLADLDAT | ||||||
Region | 392-495 | PFYRE | ||||
Sequence: VAINSVFELHRLLSRPGAIEKVLNSIKQINPKIVTLVEQEANHNAGVFIDRFNEALHYYSTMFDSLESSGSSSSASPTGILPQPPVNNQDLVMSEVYLGRQICN | ||||||
Motif | 400-404 | LXXLL motif | ||||
Sequence: LHRLL | ||||||
Region | 498-574 | SAW | ||||
Sequence: ACEGSDRVERHETLNQWRVRMNSSGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENDGCLMLGWHTRPLIATSAWK |
Domain
The DELLA motif is required for its GA-induced degradation.
Sequence similarities
Belongs to the GRAS family. DELLA subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length588
- Mass (Da)64,526
- Last updated2003-10-01 v1
- Checksum1EDADAF6BE100621
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-16 | Basic and acidic residues | ||||
Sequence: MKRDRDRDREREKRAF | ||||||
Compositional bias | 158-177 | Polar residues | ||||
Sequence: DSNKRHRSTTSSFSTTSSSM |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY269087 EMBL· GenBank· DDBJ | AAP22369.1 EMBL· GenBank· DDBJ | mRNA |