Q79VE0 · ECTP_CORGL

Function

function

Involved in the uptake of osmoprotectants. Can transport ectoine, proline and glycine betaine. Na+ is probably the coupling ion.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
63 μMectoine
333 μMglycine betaine
1200 μMproline
9100 μMNa+
Vmax pH TEMPERATURE[C] NOTES EVIDENCE
27 nmol/min/mgwith ectoine as substrate
34 nmol/min/mgwith glycine betaine as substrate
34 nmol/min/mgwith proline as substrate

Temperature Dependence

Optimum temperature is 25 degrees Celsius (irrespective of the state of osmotic stimulation).

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionsymporter activity
Biological Processamino acid transport
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Ectoine/glycine betaine/proline transporter EctP

Gene names

    • Name
      ectP
    • Ordered locus names
      Cgl2312

Organism names

Accessions

  • Primary accession
    Q79VE0
  • Secondary accessions
    • H7C678
    • O86143

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane24-44Helical
Transmembrane62-82Helical
Transmembrane102-122Helical
Transmembrane156-176Helical
Transmembrane207-227Helical
Transmembrane240-260Helical
Transmembrane275-295Helical
Transmembrane329-349Helical
Transmembrane360-380Helical
Transmembrane417-437Helical
Transmembrane463-483Helical
Transmembrane489-509Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004417311-615Ectoine/glycine betaine/proline transporter EctP

Expression

Induction

Constitutively expressed (PubMed:9811661).
Induced upon hyperosmotic conditions, but the already high maximal uptake capacity is not further elevated, indicating that the amount of EctP is not changed (PubMed:17390131).

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias524-544Basic and acidic residues
Region524-562Disordered
Region589-615Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    615
  • Mass (Da)
    67,403
  • Last updated
    2004-07-05 v1
  • Checksum
    832D85A58CA14FE7
MSSNIAITTEPEGKNKKGLKSDPFIFSISVGFIVVFVIATIALGEKARTTFSAIAGWLLENLGWMYIGGVSLVFIFLMGIFASRYGRVKLGDDDDDPEHTLIVWFCMLFAGGVGAVLMFWGVAEPINHAFNVPMANEESMSEAAIVQAFAYTFYHFGIHMWVIMALPGLSLGYFIYKRKLPPRLSSVFSPILGKHIYSTPGKLIDVLAIVGTTFGIAVSVGLGVLQINAGMNKLWSTPQVSWVQLLIILIITAVACISVASGLDKGIKLLSNINIAMAVALMFFILFTGPTLTLLRFLVESFGIYASWMPNLMFWTDSFQDNPGWQGKWTVFYWAWTICWSPYVGMFVARISRGRTVREFIGGVLALPAIFGVVWFSIFGRAGIEVELSNPGFLTQPTVVEGDVPAALFNVLQEYPLTGIVSAFALVIIVIFFITSIDSAALVNDMFATGAENQTPTSYRVMWACTIGAVAGSLLIISPSSGIATLQEVVIIVAFPFFLVQFVMMFSLLKGMSEDAAAVRRVQTRQWEKTDTPEKLEEHSSQPAPGYDDEGNPLPMPALEHDEDGNIVIPGNVVIEGDLGVVGDVVDDPEEAQEMGSRFKIVEQTRPQSRDEYDI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias524-544Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ001436
EMBL· GenBank· DDBJ
CAA04760.1
EMBL· GenBank· DDBJ
Genomic DNA
BA000036
EMBL· GenBank· DDBJ
BAB99705.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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