Q73YM4 · TRPD_MYCPA

Function

function

Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site1045-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site104anthranilate 1 (UniProtKB | ChEBI)
Binding site107-1085-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site1125-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site114-1175-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site116Mg2+ 1 (UniProtKB | ChEBI)
Binding site132-1405-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site135anthranilate 1 (UniProtKB | ChEBI)
Binding site1445-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site190anthranilate 2 (UniProtKB | ChEBI)
Binding site248Mg2+ 2 (UniProtKB | ChEBI)
Binding site249Mg2+ 1 (UniProtKB | ChEBI)
Binding site249Mg2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionanthranilate phosphoribosyltransferase activity
Molecular Functionmagnesium ion binding
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Anthranilate phosphoribosyltransferase
  • EC number

Gene names

    • Name
      trpD
    • Ordered locus names
      MAP_1931c

Organism names

Accessions

  • Primary accession
    Q73YM4

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002271691-367Anthranilate phosphoribosyltransferase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-24Disordered

Sequence similarities

Belongs to the anthranilate phosphoribosyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    367
  • Mass (Da)
    37,729
  • Last updated
    2004-07-05 v1
  • Checksum
    05F73559DB6DAEFE
MALSSESSAASAARRPSGGPATSWRQVLARLTGGDDLARGQAAWAMDQIMTGEASPAQIAAFAVAMQVKVPTSAEVIELAEVMLNHALPFPAGAIRDDTVDIVGTGGDGVNTLNLSTMAAIVAAAAGVPVVKHGNRAASSLSGGADTLEELGVRIDLGPEQVARSVAEVGIGFCFAPLFHPSYRHTSAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFAELAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVQAGTVDRLTFDPAGFGFPRAELDDLLGGDAQTNAAEVRAVLAGGQGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEDGLARASAAIDSGAAEQLLARWVRFGQQL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE016958
EMBL· GenBank· DDBJ
AAS04248.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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